This podcast will help pathologists gain deeper skills in improving HER2 IHC testing in patients with breast cancer. and includes the following topics:Optimizing IHC scoring across the HER2 spectrum in patients with breast cancerGuidelines for conducting IHC and ISH testing of HER2 in patients with breast cancerApplication through cases of patients with breast cancer along the lower spectrum of HER2 expressionSuggestions for effective coordination and collaboration among pathologists, oncologists, and other key members of the cancer care teamThe activity offers 0.75 CME/CMLE credit.Learning Objectives:Upon completion of this activity, you should be able to:Appropriately score HER2 levels via immunohistochemistry (IHC) in routine and complex breast cancer cases in accordance with guidelinesDescribe the factors that may affect IHC performance across the HER2 spectrumUtilize in situ hybridization (ISH) testing in breast cancer cases when appropriate in accordance with guidelinesDiscuss ways to prepare laboratories and cancer centers for HER2-low breast cancer identification, tracking, and reportingFaculty:Aysegul A Sahin, MDDirector of Educational OperationsDepartment of Pathology, Division of Pathology/Lab MedicineThe University of Texas MD Anderson Cancer CenterHouston, TXAli Brown, MD, FASCPChief Officer, Medical QualityAmerican Society for Clinical PathologyWashington, DCErin Downs-Kelly, DODirector, Breast PathologyCleveland ClinicCleveland, OHThe American Society for Clinical Pathology (ASCP) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education (CME) for physicians.Credit Designation StatementThe ASCP designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only credit commensurate with the extent of their participation in the activity.ASCP designates this enduring material for a maximum of 0.75 CMLE credit. This activity meets CMP and state re-licensure requirements for laboratory personnel.For questions regarding CME credit, please contact ASCP Customer Service at 1-800-267-2727, during normal business hours: Monday through Friday, 8 a.m. to 6 p.m. Eastern TimeMethod of ParticipationTo complete the activity and receive credit, the participant must complete the online course. CME certificates will be provided on-line.Provided by the American Society for Clinical Pathology in partnership with Q-Synthesis, LLC and Clinical Care Options, LLC.Funded by independent educational grants from AstraZeneca Pharmaceuticals and Daiichi Sankyo, Inc.

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