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Neurology Minute

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AAN Fall Conference 2019

04 Sep 2019

Contributed by Lukas

Dr. Jonathan Graff-Radford discusses highlights of the upcoming AAN Fall Conference in Las Vegas.

Acute nerve agent poisoning

03 Sep 2019

Contributed by Lukas

Dr. Jonathan Newmark discusses the main takeaways on acute nerve agent poisoning.

Detection of brain activation in unresponsive patients with acute brain injury

02 Sep 2019

Contributed by Lukas

Dr. Jan Claassen discusses the main takeaways from his NEJM paper on detection of brain activation in unresponsive patients with acute brain injury.

CMS proposal of new payment rule

30 Aug 2019

Contributed by Lukas

Dr. Jason Crowell discusses important changes to the CMS' new proposed payment rule.

Continuum Pearls: Tremor, pt. 3

29 Aug 2019

Contributed by Lukas

Dr. Elan Louis discusses tremor in the third part of a three-part series. To learn more, read the article "Tremor" by Dr. Louis in the August 2019 Mov...

Continuum Pearls: Tremor, pt. 2

28 Aug 2019

Contributed by Lukas

Dr. Elan Louis discusses tremor in the second part of a three-part series. To learn more, read the article "Tremor" by Dr. Louis in the August 2019 Mo...

Zika update 2019

26 Aug 2019

Contributed by Lukas

Dr. Amanda Grenell discusses the main takeaways from her Zika virus update.

Tackling the imposter phenomenon and addressing disparities for women in neurologic practice

23 Aug 2019

Contributed by Lukas

Dr. Jason Crowell highlights a commentary in Neurology: Clinical Practice on the imposter phenomenon and advancing women in neurology practice. You ca...

New FDA approval of sIRNA therapies

22 Aug 2019

Contributed by Lukas

Dr. Jeff Ratliff discusses FDA approval of new sIRNA therapies.

Continuum Pearls: Tremor

21 Aug 2019

Contributed by Lukas

Dr. Elan Louis discusses tremor in the first part of a three-part series. To learn more, read the article "Tremor" by Dr. Louis in the August 2019 Mov...

A new paraneoplastic biomarker

20 Aug 2019

Contributed by Lukas

Dr. Anastasia Zekeridou discusses the main takeaways from her paper on a new paraneoplastic biomarker. 

"Evergreen" Drug Prices

19 Aug 2019

Contributed by Lukas

Prof. Robin Feldman discusses "evergreen" drug pricing, from her paper in the Journal of Law and the Biosciences, which you can read here: https://ac...

Sex in Parkinson disease

14 Aug 2019

Contributed by Lukas

Dr. Jill Farmer offers tips to give patients related to sex in Parkinson disease.

Impulse control and RBD in PD

13 Aug 2019

Contributed by Lukas

Dr. Michele Hu and discuss the take-home message from her and Dr. David Okai's paper on a longitudinal study of the severity of impulse control disor...

CRISPR babies

12 Aug 2019

Contributed by Lukas

Dr. Heidi Ledford, senior science reporter for Nature, discusses the next steps in gene editing technology.

Non-motor symptoms of Parkinson disease

09 Aug 2019

Contributed by Lukas

Dr. Jill Farmer discusses recognition and treatment of non-motor symptoms of Parkinson disease.

Galcanezumab in cluster headache

08 Aug 2019

Contributed by Lukas

Dr. Teshamae Monteith discusses the use of galcanezumab in the treatment of cluster headache.

Managing Parkinson disease and "on and off" phenomena

07 Aug 2019

Contributed by Lukas

Dr. Jill Farmer discusses "on" and "off" phenomena of Parkinson management.

GAD Deposition in MS MRIs

06 Aug 2019

Contributed by Lukas

Dr. Robert Zivadinov discusses the main takeaways from his paper on how cumulative gadodiamide administration leads to brain gadolinium deposition in ...

Cervical Dystonia Network Localization

05 Aug 2019

Contributed by Lukas

Dr. Michael D. Fox discusses the main takeaways from his paper on cervical dystonia. You can read the paper here: https://academic.oup.com/brain/art...

IVIG therapy and use

02 Aug 2019

Contributed by Lukas

Dr. Rae Bacharach discusses intravenous or subcutaneous immunoglobulin therapy in immune-mediated neurologic conditions.

Application of the McDonald criteria in the diagnosis of MS

01 Aug 2019

Contributed by Lukas

Dr. Rae Bacharach discusses important points regarding application of the 2017 McDonald criteria for the diagnosis of MS. 

Oligoclonal bands and differentiation

31 Jul 2019

Contributed by Lukas

Dr. Rae Bacharach discusses oligoclonal bands in MS and other conditions and differentiating types of bands.

CDC's Guideline on Pediatric Mild Traumatic Brain Injury: Recommendations for Neurologists

30 Jul 2019

Contributed by Lukas

Dr. Barbara Weissman discusses the main points from her Neurology: Clinical Practice paper on recommendations for neurologists on the CDC's Guideline ...

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

29 Jul 2019

Contributed by Lukas

Dr. Geoffrey Donnan discusses the main takeaways from his study on thrombolysis guided by perfusion imaging up to 9 hours after onset of stroke. Read ...

Continuum Pearls: Disease-Modifying Therapies in MS

25 Jul 2019

Contributed by Lukas

Dr. Robert H. Gross discusses disease-modifying therapies in MS in the third part of a three-part series. To learn more, read the article "Monitoring,...

Continuum Pearls: Disease-Modifying Therapies in MS, pt. 2

24 Jul 2019

Contributed by Lukas

Dr. Robert H. Gross discusses disease-modifying therapies in MS in the second part of a three-part series. To learn more, read the article "Monitoring...

Determining clinically meaningful decline in preclinical Alzheimer disease

23 Jul 2019

Contributed by Lukas

Dr. Philip Insel provides the main findings of his paper on determining clinically meaningful decline in preclinical Alzheimer disease. 

Targeting Huntington Expression in Patients with Huntington's Disease

22 Jul 2019

Contributed by Lukas

Dr. Sarah Tabrizi discusses the main findings of her study on targeting Huntington expression in patients with Huntington's Disease. Ready the May 6th...

Continuum Pearls: Disease-Modifying Therapies in MS

19 Jul 2019

Contributed by Lukas

Dr. Robert H. Gross discusses disease-modifying therapies in MS in the first part of a three-part series. To learn more, read the article "Monitoring,...

Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial, pt. 2

17 Jul 2019

Contributed by Lukas

Prof. Gil Wolfe discusses who might and might not be good candidates for thymectomy for non-thymomatous myasthenia gravis in the second part of his in...

The full spectrum of epilepsies from SUDEP in the North American SUDEP Registry

16 Jul 2019

Contributed by Lukas

Dr. Orrin Devinsky summarizes his paper on the full spectrum of epilepsies and the North American SUDEP Registry. Listen to this week's full podcast f...

Long-term effect of thymectomy plus prednisone versus prednisone alone in patients with non-thymomatous myasthenia gravis: 2-year extension of the MGTX randomised trial

15 Jul 2019

Contributed by Lukas

Prof. Gil Wolfe summarizes his findings from his study on the long-term effect of thymectomy plus prednisone versus prednisone alone in patients with ...

Neurology Residency Programs & Training

12 Jul 2019

Contributed by Lukas

Dr. Jeffrey Ratliff discusses neurology residency programs, training, and action by the consortium of residency program directors.

MuSK Myasthenia Gravis

11 Jul 2019

Contributed by Lukas

Dr. Ted Burns discusses clinical recognition and diagnosis of MuSK myasthenia gravis.

Continuum Pearls: Pregnancy and Family Planning in Multiple Sclerosis, pt. 3

10 Jul 2019

Contributed by Lukas

Dr. Annette Langer-Gould discusses pregnancy and family planning with MS in the third of a three-part series. To learn more, read the article "Pregnan...

Use of ß2-adrenoreceptor agonist and antagonist drugs and risk of Parkinson disease

09 Jul 2019

Contributed by Lukas

Dr. Franziska Hopfner talks about the main takeaways from her paper on the use of ß2-adrenoreceptor agonist and antagonist drugs and risk of Parkinso...

First Cannabis-Derived Pharmaceutical

08 Jul 2019

Contributed by Lukas

Dr. Jerzy Szaflarski talks about the FDA's approval of the first cannabis-derived pharmaceutical for the treatment of epilepsy and Lennox-Gastaut syn...

Sports Concussion Conference 2019

05 Jul 2019

Contributed by Lukas

Co-director Dr. Brian Hainline talks about new features and highlights of the 2019 AAN Sports Concussion Conference. The conference takes place July 2...

Continuum Pearls: Pregnancy and Family Planning in MS, pt. 2

04 Jul 2019

Contributed by Lukas

Dr. Annette Langer-Gould discusses pregnancy and family planning with MS in the second part of a three-part series. To learn more, read the article "P...

Continuum Pearls: Pregnancy and Family Planning in Multiple Sclerosis, pt. 1

03 Jul 2019

Contributed by Lukas

Dr. Annette Langer-Gould discusses pregnancy and family planning with MS in the first of a three-part series. To learn more, read the article "Pregnan...

Current treatment practice of Guillain-Barré syndrome

02 Jul 2019

Contributed by Lukas

Dr. Michelle Mauermann talks with Dr. Bart Jacobs about his paper on current treatment practice of Guillain-Barré syndrome.

Somatic expansion of the C9orf72 repeat

01 Jul 2019

Contributed by Lukas

Dr. Guy Rouleau discusses the main takeaways from his Neurology: Genetics paper on how the somatic expansion of the C9orf72 Hexanucleotide repeat does...

Brian Dodick discusses the 2019 Sports Concussion Conference

28 Jun 2019

Contributed by Lukas

Dr. Brian Dodick discusses highlights of the upcoming 2019 Sports Concussion Conference in Indianapolis.

Continuum Pearls: Diagnosis, Differential Diagnosis, and Misdiagnosis of Multiple Sclerosis, pt. 2

27 Jun 2019

Contributed by Lukas

Dr. Andrew J. Solomon discusses the diagnosis of multiple sclerosis in the second of a three-part series. To learn more, read the article "Diagnosis, ...

Continuum Pearls: Diagnosis, Differential Diagnosis, and Misdiagnosis of Multiple Sclerosis

26 Jun 2019

Contributed by Lukas

Dr. Andrew J. Solomon discusses the diagnosis of multiple sclerosis in the first of a three-part series. To learn more, read the article "Diagnosis, D...

Interview with Dr. Bob Gross, pt. 2

25 Jun 2019

Contributed by Lukas

Dr. Gross discusses a challenging experience from his time as Editor-in-Chief of Neurology, from the longer second part of the interview available thr...

Continuum Pearls: NMOSD and other CNS inflammatory diseases, pt. 3

24 Jun 2019

Contributed by Lukas

Dr. Eoin Flanagan discusses NMOSD in the third of a three-part series. To learn more, read the article "Neuromyelitis Optica Spectrum Disorder and Oth...

Neurology Today Highlight: antisense oligonucleotide therapy for variant of Batten disease

21 Jun 2019

Contributed by Lukas

Dr. Jason Crowell discusses Richard Robinson's article on an antisense oligonucleotide therapy for a rare variant of Batten Disease. To learn more, re...

Continuum Pearls: NMOSD and other CNS inflammatory diseases, pt. 2

20 Jun 2019

Contributed by Lukas

Dr. Eoin Flanagan discusses NMOSD in the second of a three-part series. To learn more, read the article "Neuromyelitis Optica Spectrum Disorder and Ot...

Continuum Pearls: NMOSD and other CNS inflammatory diseases, pt. 1

19 Jun 2019

Contributed by Lukas

Dr. Eoin Flanagan discusses NMOSD in the first of a three-part series. To learn more, read the article "Neuromyelitis Optica Spectrum Disorder and Oth...

Dr. Bob Gross discusses changes in publishing & media

17 Jun 2019

Contributed by Lukas

Dr. Bob Gross, Editor-in-Chief of the Neurology family of journals, discusses changes in publishing and media as well as how the journal will differen...

Continuum Pearls: Driving and Epilepsy: Ethical, Legal, and Health Care Policy Challenges, pt. 2

14 Jun 2019

Contributed by Lukas

Dr. Joseph Kass discusses driving and epilepsy in the second of a three-part series. To learn more, read the article "Driving and Epilepsy: Ethical, L...

Continuum Pearls: Driving and Epilepsy: Ethical, Legal, and Health Care Policy Challenges, pt. 1

13 Jun 2019

Contributed by Lukas

Dr. Joseph Kass discusses driving and epilepsy in the first of a three-part series. To learn more, read the article "Driving and Epilepsy: Ethical, Le...

Continuum Pearls: Nonepileptic Episodic Events, Pt. 3

12 Jun 2019

Contributed by Lukas

Dr. Jennifer Hopp discusses treating patients with nonepileptic episodic events in the third of a three-part series. To learn more, read the article "...

Lumbosacral Radiculoplexus Neuropathy: Incidence and the Association with Diabetes Mellitus

11 Jun 2019

Contributed by Lukas

Dr. P. James B. Dyck discusses takeaways about his paper, from the March 12th issue, on the incidence of lumbrosacral radiculoplexus neuropathy and as...

Continuum Pearls: Nonepileptic Episodic Events, Pt. 2

07 Jun 2019

Contributed by Lukas

Dr. Jennifer Hopp discusses nonepileptic episodic events in the second of a three-part series. To learn more, read the article "Nonepileptic Episodic ...

Continuum Pearls: Non-Epileptic Episodic Events, Pt. 1

06 Jun 2019

Contributed by Lukas

Dr. Jennifer Hopp discusses differentiating epileptic versus nonepileptic events in the first of a three-part series. To learn more, read the article ...

Continuum Pearls: Treatment of Women with Epilepsy, pt. 3

05 Jun 2019

Contributed by Lukas

Dr. Mona Sazgar discusses tips for treating menopausal women with epilepsy in the third of a three-part series. To learn more, read the article "Treat...

Opioid prescribing and response to the CDC guidelines

03 Jun 2019

Contributed by Lukas

Dr. Deborah Dowell discusses takeaways on her article on opioid prescribing and safe treatment. 

Continuum Pearls: Treatment of Women with Epilepsy, Pt. 2

31 May 2019

Contributed by Lukas

Dr. Mona Sazgar discusses tips for treating women with catamenial epilepsy in the second of a three-part series. To learn more, read the article "Trea...

Continuum Pearls: Treatment of Women with Epilepsy, Pt. 1

30 May 2019

Contributed by Lukas

Dr. Mona Sazgar discusses tips for treating women with epilepsy in the first of a three-part series. To learn more, read the article "Treatment of Wom...

Approach to Diagnosing Genetic Ataxias

29 May 2019

Contributed by Lukas

Dr. Stephan Pulst discusses approaches to diagnosing genetic ataxias. 

Rising Out-of-Pocket Costs for Common Neurologic Medications

28 May 2019

Contributed by Lukas

Dr. Brian Callaghan talks about the rise in out-of-pocket costs for commonly prescribed neurologic medications. 

Continuum Pearls: Optimizing Management of Medically Responsive Epilepsy, Part 3

27 May 2019

Contributed by Lukas

Dr. Derek Bauer discusses how to optimize epilepsy management. To learn more, read the article "Optimizing Management of Medically Responsive Epilepsy...

Continuum Pearls: Optimizing Management of Medically Responsive Epilepsy, Part 2

24 May 2019

Contributed by Lukas

Dr. Derek Bauer offers tips for epilepsy neurologists with more experience in optimizing epilepsy management. To learn more, read the article "Optimiz...

Continuum Pearls: Optimizing Management of Medically Responsive Epilepsy

23 May 2019

Contributed by Lukas

Dr. Derek Bauer discusses optimizing management of medically responsive epilepsy. To learn more, read the article "Optimizing Management of Medically ...

Continuum Pearls: Important Takeaways in Evaluating Seizure Etiology

22 May 2019

Contributed by Lukas

Dr. Stephan U. Schuele offers important takeaways in evaluating seizure etiology. To learn more, read the article "Evaluation of Seizure Etiology fro...

Long-term Outcomes of NeuroZika

21 May 2019

Contributed by Lukas

Dr. Stacey Clardy discusses discusses takeaways from Dr. Annie Lannuzel's paper on the long-term outcomes of NeuroZika. 

Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors (NEJM)

20 May 2019

Contributed by Lukas

Dr. Stuart Connolly discusses the main takeaways from his NEJM paper on andexanet alfa for Bleeding Associated with Factor Xa Inhibitors. Read the pa...

Talking to Legislators on PCORI

17 May 2019

Contributed by Lukas

Dr. Jason Crowell discusses the importance of talking to legislators about PCORI. Share your story on the AAN Advocacy Action Center at https://www.a...

Continuum Pearls: Evaluating Seizure Etiology, pt. 2

16 May 2019

Contributed by Lukas

Dr. Stephan U. Schuele discusses the evaluation of seizure etiology for neurologists with more experience. To learn more, read the article "Evaluatio...

Continuum Pearls: Evaluation of Seizure Etiology From Routine Testing to Genetic Evaluation

15 May 2019

Contributed by Lukas

Dr. Stephan U. Schuele discusses the evaluation of seizure etiology. To learn more, read the article "Evaluation of Seizure Etiology from Routine Tes...

Meta-analysis and cost-effectiveness of second-line antiepileptic drugs for status epilepticus

14 May 2019

Contributed by Lukas

Dr. Ivan Sanchez Fernandez discusses the main points from his paper on meta-analysis and cost-effectiveness of second-line antiepileptic drugs for sta...

Measles in 2019 with Dr. Anthony Fauci

13 May 2019

Contributed by Lukas

Dr. Anthony Fauci discusses the main points on his paper on measles in 2019. "Measles in 2019--Going Backward" can be found in the New England Journal...

STEP Therapy & Results of AAN Advocacy Efforts for Patients with Neurological Disease

10 May 2019

Contributed by Lukas

Dr. Jason Crowell discusses STEP therapy and recent advocacy efforts by the AAN at Neurology on the Hill. Read the AAN Capitol Hill Report from April ...

Continuum Pearls: Posterior Cortical Atrophy

08 May 2019

Contributed by Lukas

Dr. Jonathan Graff-Radford, guest editor of the February 2019 Continuum Dementia issue, discusses posterior cortical atrophy. To learn more, read th...

Treatment of Tics and People with Tourette's Syndrome

07 May 2019

Contributed by Lukas

Dr. Tamara Pringsheim discusses guideline recommendations on assessment and management of tics in people with Tourette's Syndrome and chronic tic diso...

Regulation on Human Gene Editing

06 May 2019

Contributed by Lukas

New York Times staff writer Pam Belluck discusses the WHO and regulation on human gene editing. Read her March 19, 2019, article here: https://www.ny...

Drug Prices for Lambert Eaton Myasthenic Syndrome

03 May 2019

Contributed by Lukas

Dr. Jason Crowell discusses skyrocketing costs of a drug used for treatment with Lambert-Eaton myasthenic syndrome. 

Medical Clerkships in Neurology

02 May 2019

Contributed by Lukas

Dr. Rae Bacharach discusses trends in medical clerkships in neurology.

Continuum Pearls: Early-onset Alzheimer Disease

01 May 2019

Contributed by Lukas

Dr. Jonathan Graff-Radford, guest editor of the February 2019 Continuum Dementia issue, discusses early-onset Alzheimer Disease. To learn more, read ...

Dr. Jenny Linnoila discusses: Mouse model of anti-NMDA receptor post–herpes simplex encephalitis

30 Apr 2019

Contributed by Lukas

Dr. Jenny Linnoila discusses the main takeaways from her podcast interview and paper on a mouse model of anti-NMDA receptor post-herpes simplex enceph...

Gene Editing and CRISPR

29 Apr 2019

Contributed by Lukas

Pam Belluck of the New York Times discusses He Jiankui, gene editing and CRISPR. Read one of the articles on the issue here: https://www.nytimes.com/...

New FDA-Approved Treatments for MS

25 Apr 2019

Contributed by Lukas

Dr. Rae Bacharach discusses two new, disease-modifying therapies for use in multiple sclerosis.

Continuum Pearls: Transient Epileptic Amnesia

24 Apr 2019

Contributed by Lukas

Dr. Gregory Day discusses the recognition of transient epileptic amnesia. To learn more, read Dr. Day's article, "Reversible Dementias," in the Februa...

Montreal Cognitive Assessment as a screening tool: Influence of performance and symptom validity

23 Apr 2019

Contributed by Lukas

Dr. Brigid Waldron-Perrine talks about the Montreal Cognitive Assessment as a screening tool.

Use of Neurofilament Light as a Potential Biomarker for Alzheimer's Disease

22 Apr 2019

Contributed by Lukas

Dr. Mathias Jucker discusses the use of neurofilament light as a potential biomarker for Alzheimer's Disease.

Continuum Pearls: Behavioral Variant Frontotemporal Dementia

17 Apr 2019

Contributed by Lukas

Dr. Jonathan Graff-Radford, guest editor of the February 2019 Dementia issue of Continuum, discusses behavioral-variant frontotemporal dementia. To le...

The comparative effectiveness of teriflunomide and dimethyl fumarate

16 Apr 2019

Contributed by Lukas

Dr. Mathias Buron discusses the takeaways from his paper the comparative effectiveness of teriflunomide and dimethyl fumarate.

Joanna Hellmuth: The Rise of Pseudomedicine for Dementia and Brain Health

15 Apr 2019

Contributed by Lukas

Dr. Joanna Hellmuth discusses the findings of her paper on the rise of pseudomedicine for dementia and brain health.  

65-year-old female with subacute hemiballism

11 Apr 2019

Contributed by Lukas

Dr. Roy Strowd discusses a recent Clinical Reasoning case about a 65-year-old female with subacute hemiballism. 

Continuum Pearls: Hippocampal Sclerosis of Aging

10 Apr 2019

Contributed by Lukas

Dr. Jonathan Graff-Radford, guest editor of the February 2019 Dementia issue of Continuum, discusses hippocampal sclerosis of aging. To learn more, re...

How much periventricular lesions assist in distinguishing migraine with aura from CIS?

09 Apr 2019

Contributed by Lukas

Dr. Caterina Lapucci talks about her paper addressing how much periventricular lesions assist in distinguishing migraine with aura from CIS. 

Drug Pricing and Drug Pricing Legislation

08 Apr 2019

Contributed by Lukas

Sarah Karlin-Smith and Sarah Owermohle from Politico talk about drug pricing and legislation to affect drug pricing.

Pregnant Woman Presents with Chin Numbness

04 Apr 2019

Contributed by Lukas

Dr. Roy Strowd showcases a Clinical Reasoning case on a pregnant woman presenting with chin numbness.

Continuum Pearls: Practical Approach to Recognizing Patients with Reversible Dementia

03 Apr 2019

Contributed by Lukas

Dr. Gregory Day offers a practical approach to recognizing patients with reversible dementia. To learn more, read Dr. Day's article, "Reversible Demen...

Automated seizure detection accuracy for ambulatory EEG recordings

02 Apr 2019

Contributed by Lukas

Dr. Stephan Schuele discusses the main takeaways from his paper on automated seizure detection accuracy for ambulatory EEG recordings. 

SHINE Stroke Trial

01 Apr 2019

Contributed by Lukas

Dr. Kevin Barrett discusses the SHINE stroke trial, which was designed to determine the optimal treatment of hyperglycemia in acute stroke.

Preview of 2019 AAN Annual Meeting

29 Mar 2019

Contributed by Lukas

Dr. Joe Sirven previews the upcoming 2019 AAN Annual Meeting in Philadelphia.

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