NPR News: 10-10-2025 4PM EDT

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NPR News Now 4 min 6 speakers 6 chapters transcribed 2 months ago
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What happened in the Tennessee explosion and its impact?

Jorge Sedano 0:00
Support for NPR comes from NPR member stations and Eric and Wendy Schmidt through the Schmidt Family Foundation, working toward a healthy, resilient, secure world for all. On the web at theschmidt.org.
Janine Herbst 0:15
Live from NPR News in Washington, I'm Janine Hurst. In Tennessee, authorities say at least 19 people are missing and feared dead after an explosion at a military munitions plant in Bucksnort, about 60 miles west of Nashville this morning. Several people were hospitalized. Humphrey County Sheriff Chris Davis was asked to describe the scene.
Can I describe the building? There's nothing to describe. It's gone. Again, it's the most devastating scene that I've seen in my career.

What are the implications of federal worker layoffs during the government shutdown?

Janine Herbst 0:46
Davis says they feel the scene is secure and that the ATF and FBI are investigating, but right now there's no word on a cause. He says they expect to be there for days. The blast was reportedly felt 10 miles from the plant that manufactured, stored, and researched explosive materials. White House Budget Director Russell Vogt says layoffs of federal workers began today. This follows President Trump's threats to fire workers and close agencies if the federal government shutdown continues. It's now on its 10th day with no end in sight. Secretary of Defense Pete Hegseth says the U.S. will build a Qatari Air Force facility in the U.S. And Pierce Quill Lawrence has more.
Quill Lawrence 1:26
Hegseth praised Qatar's substantial role in brokering President Trump's Gaza peace deal, which is in the early stages of implementation.

How is the U.S. collaborating with Qatar on military facilities?

Pete Hegseth 1:34
Hegseth added, I'm also proud that today we're announcing, we're signing a letter of acceptance to build a Qatari-Emeri Air Force facility at the Mountain Home Air Base in Idaho.
Quill Lawrence 1:45
He said the base will host a contingent of Qatari F-15s and pilots in continuation of a long military partnership between the two countries. The U.S. has relied on Qatar to base troops in the Middle East for decades. This year, the Trump administration has drawn criticism from ethics watchdogs over accepting a gift from Qatar of a half-billion-dollar luxury jet intended to be a replacement for Air Force One. Quill Lawrence, NPR News.
Janine Herbst 2:10
MIT says it won't be signing a Trump administration letter in exchange for federal funding. And here's Alyssa Nadworny has more.
Alyssa Nadworny 2:18
The letter from MIT President Sally Kornbluth says the compact quote includes principles with which we disagree. MIT was one of nine universities asked by the Department of Education to sign the agreement to ensure access to federal funding and grants.

What is MIT's stance on the Trump administration's funding compact?

Alyssa Nadworny 2:32
The compact requires schools to agree to a list of demands, including a five-year tuition rate freeze, limits on international students, and prohibiting the use of race or sex as admissions factors. Kornbluth writes the university believes that scientific funding should be based on scientific merit alone, and therefore, quote, we cannot support the proposed approach to addressing the issues facing higher education. The university is the first school to respond publicly to the administration's compact. Alyssa Nadworny, NPR News.
Janine Herbst 3:02
Wall Street sharply lowered by the close after President Trump threatened higher tariffs on China, accusing the country of becoming very hostile with restrictions on rare earth metals. Dow down 878 points. This is NPR. Scientists are hoping to treat diseases, including Alzheimer's, by influencing the way cells decide when to die. NPR's John Hamilton has more on efforts to control the process known as programmed cell death.
Carrington Clark 3:30
In Alzheimer's and other neurodegenerative diseases, nerve cells decide to self-destruct long before they should.

How are scientists addressing programmed cell death in diseases like Alzheimer's?

Carrington Clark 3:36
So biotech companies are looking for ways to keep these cells alive by blocking signals that start the fatal process. Doug Green of St. Jude Children's Research Hospital says several firms think they can do this with treatments known as antisense drugs.
If they're right, it's going to cure a lot of diseases. Diseases that we associate with aging and inflammation.
Carrington Clark 3:57
Antisense drugs can keep a cell from making certain proteins. In this case, the drugs are designed to reduce proteins that carry the signals responsible for programmed cell death.

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