This week on the Osterholm Update, Chris Dall and Dr. Osterholm dissect the latest results of Paxlovid trials and what they tell us about COVID-19. They'll also discuss a CDC study on COVID-19 vaccines that's been blocked by the acting CDC director, examine a survey that reveals the impact of changes to CDC messaging on vaccines and autism, explore the US Defense Secretary's decision to no longer require flu shots for US military members and bring you up to speed on the hantavirus outbreak on a Dutch cruise ship. Plus, the latest findings of CIDRAP’s analysis of HPV vaccines. <a href="https://www.cidrap.umn.edu/covid-19/paxlovid-doesn-t-reduce-hospitalization-death-rates-vaccinated-high-risk-covid-outpatients">Paxlovid doesn’t reduce hospitalization, death rates in vaccinated high-risk COVID outpatients, trial shows</a> (CIDRAP) <a href="https://insidemedicine.substack.com/p/the-end-of-the-paxlovid-era-why-two">The end of the Paxlovid era? Why two new negative trials are great news.</a> (Inside Medicine Substack)    <a href="https://www.statnews.com/2026/04/27/is-covid-still-a-thing-expert-analysis-who-needs-vaccine-booster-shot/">What happened to Covid?</a> (STAT) <a href="https://vaxintegrity.cidrap.umn.edu/sites/default/files/FINAL%20REPORT%20HPV%20Vaccine%20Evidence%20Review_0.pdf">Safety and effectiveness of human papillomavirus (HPV) vaccine</a> (Vaccine Integrity Project) <a href="https://www.cidrap.umn.edu/human-papillomavirus-hpv/hardest-thing-i-ve-ever-gone-through-cervical-cancer-survivors-speak-out">‘The hardest thing I’ve ever gone through’: Cervical cancer survivors speak out about importance of HPV vaccine</a> (CIDRAP)   Resources for vaccine and public health advocacy: <a href="https://www.voicesforvaccines.org/get-involved/">Voices for Vaccines</a> <a href="https://familiesfightingflu.org/take-action/">Families Fighting Flu</a> <a href="https://vaccinateyourfamily.org/get-involved/">Vaccinate Your Family</a> <a href="https://shotatlife.org/take-action/">Shot@Life</a> <a href="https://aspr.hhs.gov/MRC/Pages/index.aspx">Medical Reserve Corps</a> Learn more about the <a href="https://www.cidrap.umn.edu/vaccine-integrity-project">Vaccine Integrity Project</a> <a href="https://www.cidrap.umn.edu/covid-19/osterholm-update-covid-19">MORE EPISODES</a>       <a href="https://www.cidrap.umn.edu/support-cidrap">SUPPORT THIS PODCAST</a>   Music: "Beauty Flow" Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 4.0 License

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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