This episode is brought to you by Cozy Earth, BiOptimizers, and InsideTracker. For decades, I’ve been on a mission to help my patients understand that weight loss is not about “calories in, calories out”. There are a multitude of factors that play into how our body makes, stores, and burns fat and the actual amount of calories we eat is one small drop in the bucket of our complex biology. Today, I’m excited to talk with Dr. Casey Means about the main drivers people face when struggling to lose weight and what we can do about them. Dr. Casey Means is a Stanford-trained physician, Chief Medical Officer, and Co-founder of metabolic health company Levels, an Associate Editor of the International Journal of Disease Reversal and Prevention, and a Lecturer at Stanford University. Her mission is to maximize human potential and reverse the epidemic of preventable chronic disease by empowering individuals with tools that can facilitate a deep understanding of our bodies and inform personalized and sustainable dietary and lifestyle choices. Dr. Means’ perspective has been featured in the New York Times, Wall Street Journal, Men's Health, Forbes, Business Insider, Techcrunch, Entrepreneur Magazine, Metabolism, Endocrine Today, and more. This episode is brought to you by Cozy Earth, BiOptimizers, and InsideTracker. Cozy Earth makes the most comfortable, temperature-regulating, nontoxic sheets on the market. Right now, get 40% off your Cozy Earth sheets. Just head over to cozyearth.com and use code MARK40. Magnesium Breakthrough really stands out from the other magnesium supplements out there. BiOptimizers is offering my community 10% off, so just head over to magbreakthrough.com/hyman with code hyman10. InsideTracker is a personalized health and wellness platform like no other. Right now they’re offering my community 20% off at insidetracker.com/drhyman. Here are more details from our interview (audio version / Apple Subscriber version): The top reasons for resistance to weight loss beyond food, sleep, stress management, and exercise (5:41 / 2:30) Obesogens, obesity, and resistance to weight loss (11:41 / 8:50) Common sources of toxins in our daily lives (13:57 / 9:45) How toxins negatively affect our health (14:44 / 12:10) Why detoxification is an important component of weight loss (17:45 / 15:00) Limiting our toxic exposure (18:49 / 16:26) The role of micronutrients in resistance to weight loss (29:33 / 25:16) Tips for grocery shopping for micronutrients (40:02 / 35:50) The impact of light on our metabolism (47:29 / 43:14) Using a continuous glucose monitor to improve your metabolic health (55:36 / 51:35) For a limited time only, if you sign up for Levels at levels.link/HYMAN, you'll receive five exclusive longevity strategies from me and Dr. Casey Means.

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“What did the council decide on item 42?” — answered with the speaker and the moment.