Why Muscle, Our Neglected Organ, Is The Key To Healthy Aging | This episode is brought to you by Paleovalley When it comes to longevity, the goal isn’t just to live as long as possible. The true objective is to live as vibrantly and energetically as possible, for as long as possible. So how exactly do we do this? On this episode of The Doctor’s Farmacy, I was happy to sit down and talk with Dr. Chris Rinsch and Dr. Stuart Phillips about the role of mitochondria in aging, and how we can use various compounds that are found in plants to upregulate our biology and increase not just our lifespan, but more importantly our healthspan. Dr. Chris Rinsch is the co-founder and CEO of Amazentis, an innovative life science company dedicated to employing breakthrough research and clinical science to bring advanced therapeutic nutrition products to life. Dr. Rinsch has authored original publications in leading scientific journals, including Nature Medicine, Gene Therapy and others, for his research on Urolithin A, mitochondrial health, and cell and gene therapy. He is also an inventor on a number of internationally filed and granted patents. Dr. Rinsch holds an MBA from INSEAD, France, a PhD in Cell and Molecular Biology from the University of Lausanne, a Master of Science in Biomedical Engineering from U.T. Southwestern Medical Center, and a Bachelor of Science in Engineering from Harvey Mudd College. Dr. Stuart Phillips is a Professor in the Department of Kinesiology and a member of the School of Medicine at McMaster University. He is Tier 1 Canada Research Chair in Skeletal Muscle Health. He is also the Director of the McMaster University Physical Activity Centre of Excellence. Dr. Phillips has authored more than 220 original research papers and 90 reviews. In 2018 and 2019, he was named to Clarivate’s Highly Cited Researchers list as a being in the top 1% of all cited researchers in nutrition and exercise research. Dr. Phillips is a fellow of the American College of Sports Medicine and the Canadian Academy of Health Sciences. This episode is brought to you by Paleovalley. Right now, Paleovalley is offering my listener's 15% off your entire first order. Just go to paleovalley.com/hyman to check out all their clean Paleo products and take advantage of this deal. Here are more of the details from our interview: The role of mitochondria and muscle function in healthy aging and longevity (4:20) Why skeletal muscle is somewhat neglected in medicine ( 6:37) Improving muscle mass and function as we age (7:13) How mitochondrial function impacts heart, brain, and other tissue (10:48) Renewing mitochondria through mitophagy (15:33) Amazentis’ research on pomegranates and how it lead to an understanding of urolithin A’s effect on mitochondrial function (18:52) How the gut microbiome interacts with the compounds in the food we eat (23:57) Increasing the energy level inside the cells for optimal muscle function (27:16) The research on, and development of, Mitopure Urolithin, Amazentis’ proprietary product, and how it affects mitochondrial function (29:24) Boosting muscle health and function as we age (41:26) Learn more about Amazentis at https://www.amazentis.com/. Learn more about Timeline Nutrition and take advantage of their exclusive offer for a 2 month plan of Mitopure for $200 at www.timelinenutrition.com/drhyman Follow Timeline Nutrition on IG @timelinenutrition, on Facebook @TimelineNutrition on FB , at on Twitter @UrolithinA.

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