(Conversation recorded on January 21st, 2025) Many of us are familiar with the problem of plastics as a distant issue in the ocean, primarily affecting fish and sea turtles. While these environmental effects are critical, the full scope of plastic's repercussions on human health and well-being is largely unknown by most people, even as the research shows alarming – and growing – adverse effects. What do we need to know about this pervasive material and how it affects the human body? Today, Nate is joined by environmental health researchers Leo Trasande and Linda Birnbaum, as well as environmental policy advocate Christina Dixon, to discuss the harmful effects of plastic on human health and the ongoing global policy efforts to regulate the plastic and petrochemical industries. Their conversation dives into the risks of frequent plastic exposure, paths toward a world with reduced plastics use, and what it might mean for the economy if we made – or did not make – significant changes to the ways we use plastic. How can we balance the requirement for essential plastics with the urgent need to reduce our production and consumption of these toxic materials? What further unknown health effects are still in need of research - especially in the case of thousands of untested chemicals used on the market? Lastly, what is the current state of regulation on plastic production and consumption, and how can everyday citizens play a role in shaping the future of the plastic industry? About Leo Trasande: Dr. Leo Trasande is the Jim G. Hendrick MD Professor, Director of the Division of Environmental Pediatrics, and Vice Chair for Research in the Department of Pediatrics at NYU School of Medicine. He also serves on the faculty of the NYU Wagner School of Public Service and the NYU College of Global Public Health. Leo is an internationally renowned leader in environmental health. His research focuses on the impacts of chemicals on hormones in our bodies. He has also led the way in documenting the economic costs for policy makers of failing to prevent diseases of environmental origin proactively. About Linda Birnbaum: Linda S. Birnbaum, Ph.D., D.A.B.T., A.T.S, was director of the National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health, and the National Toxicology Program (NTP) from 2009 to 2019. As board certified toxicologist, Linda also served as a federal scientist for 40 years, including 19 years at the U.S. Environmental Protection Agency (EPA), where she directed the largest division focusing on environmental health research. Birnbaum is now a Special Volunteer at NIEHS and conducts research as part of the Mechanistic Toxicology Branch. In October 2010, she was elected to the Institute of Medicine of the National Academies, one of the highest honors in the fields of medicine and health. About Christina Dixon: Christina Dixon is a campaign leader at the Environmental Investigation Agency (EIA) in the UK, using policy, advocacy, and corporate campaigning skills towards environmental issues. Christina currently leads the EIA's plastics treaty campaign, where she oversees a diverse and highly skilled team of legal, policy and campaigning experts combating plastic (over)production & pollution, waste trade, commercial whaling, illegal marine species trade, and bycatch. Please note that, starting with this episode, Reality Roundtables will be released on Mondays going forward. Show Notes and More Watch this video episode on YouTube Want to learn the whole story of The Great Simplification? Watch our 30-minute Animated Movie. --- Support The Institute for the Study of Energy and Our Future Join our Substack newsletter Join our Discord channel and connect with other listeners

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