The Nerve with Maureen Callahan
Oprah Spends Birthday with Platonic Friend Gayle, Jillian Michaels Gets REAL About GLP-1 Lawsuits, and Amy Griffin EXPOSED
30 Jan 2026
Chapter 1: What is the main topic discussed in this episode?
Hello and welcome to your Friday edition of The Nerve. I am your host Maureen Callahan. We have a packed, packed show for you today. First up, Jillian Michaels is back, one of our favorites, to help us break down the latest on GLP-1s, all the stuff that the rest of the media won't be telling you and won't be talking about.
Plus, she's going to talk to us about the new food pyramid and Andy Cohen, really great, really, really great. Then we've got a celebrity roundup with a special Nepo edition folded in. A ton of your feedback. It's incredible. And then later in the show, we'll be talking about everything that is wrong with the book publishing industry.
It's not just Amy Griffin, but she's coming in for another whacking. Adam Zetella, author of That Book is Dangerous, is going to join us to talk about why the book publishing industry is completely after right now. Okay.
Chapter 2: What are the dangers of GLP-1 drugs discussed by Jillian Michaels?
Plagued by trigger warnings, safe spaces. book contracts for only certain kinds of people. And, you know, again, nerve recidivist, Amy Griffin, you won't believe what the book publishing industry admits about her. You won't believe it, but trust me, the nerve was right. The nerve was right. It's another packed show. Are you ready? Are you ready? Let's go.
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Chapter 3: How are celebrities influencing the normalization of GLP-1 drugs?
And if you don't feel like ordering online, Masa is now available nationwide at your local Sprouts supermarket. Stop by and pick up a couple of bags before they're gone. joining us now wellness expert and host of the must subscribe keeping it real podcast jillian michaels jillian welcome back to the nerve oh thank you it's so great to be back home with you
so um i saw this like wednesday morning and i thought of you immediately serena williams was on the today show oh boy she has nothing jillian nothing to promote nothing except except for the glp-1 company that she's now a paid show for called row and this bugs me so much because this is deception this is a pharmaceutical ad dressed up as a celebrity interview.
We're going to take a little bit of a look and then dying for your reaction. Here we go.
Chapter 4: What are the criticisms of nepo babies in social media?
Yeah. So here's the thing. Last time you were here, you partnered with Roe. You've been on GLP Ones for a minute. And I read this morning, I think this is so interesting, and you tell me if this is right, some of your numbers, like cholesterol or what have you, are better now. Yeah, isn't that crazy? Is that true?
When you were competing. When I was competing, and not just competing and just playing, but actually winning Grand Slams. Wow.
Chapter 5: What insights does Adam Szetela provide about institutional issues in publishing?
So my cholesterol level is 30% lower than it was years ago, which is insane, which I didn't even know. So if you have a high cholesterol level, you have a chance for heart disease. Yes. And that is a huge killer in the States, in the United States. So for me, I was like, was I in line to have heart disease? So what I love about GLP-1s is the longevity of health. And that's when I started this.
I was like, OK, I want to drop weight, obviously. But it was so much more to me than just dropping weight. And so getting on GLP ones with Roe and just having experience with Roe and just being able to find all these stats that are just surprising me and blowing my mind and also knowing that, OK, so I'm actually going to be able to be around for my kids longer. Like, who knows?
Who knows what all this stuff could lead to?
Jillian, I think people like you and I know what all this stuff could lead to. Oh, geez. Okay.
This is such a bummer. I actually love Serena. She's one of my favorite athletes. So to have to comment on this really just... I'm sorry. Having said that... Listen, this is America. You do what you want with your body. But cholesterol, first of all, is a very complicated conversation. And the reality is that while we know there is a correlation to cholesterol and heart disease,
That doesn't necessarily mean if you have high cholesterol, you will have arterial plaque. There's a lot of different elements there. And this is where a cardiologist should advise people. It has to do with how much low density lipids, the particle size of the low density lipids, how many small particle low density lipids.
Are you genetically predisposed to depositing these low density lipids in your arteries? There's something called a calcium score, which is fantastic. far more accurate than just a lipid panel on your blood work.
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Chapter 6: How did Oprah celebrate her 72nd birthday?
But it's a separate conversation. When it comes to these medications, if there is a halo effect when it comes to health, it's because of the weight loss. So that's going to be, for example, if I took 30 pounds off of Serena without these drugs, same benefits and probably more. So again, like if this is working for her and she's happy, Great.
You know, who am I to tell her what to do with her body? But the truth of the matter is these drugs, I've said it before and I will say it again, they have a really serious side effect profile. And you just need to know that going in, if it's absolutely something that you're incapable of doing without the medication, then it becomes a cost benefit analysis that you play out with your doctor.
Yes.
Chapter 7: What challenges exist in the publishing industry according to Maureen Callahan?
And that is my issue with that interview is that Serena's talking there as though she's very fluent in the medical, biological, biochemical effects of these drugs. And she's saying, and I'm going to live a much longer life because I'm on this GLP-1. I wanted to read to you and to you all of the troublemakers, Jillian. Yeah, let me do it. I'm sorry. Okay.
We're going to move off Serena to a dietitian who wrote to us from Texas. Okay. Okay. She says I am licensed and registered. I've been practicing for almost 20 years. I practice in the clinical setting and I have seen firsthand the devastating side effects of these medications.
We have seen such cases such as colonic perforation, acute pancreatitis, blockage in the small intestine that requires ostomy creation, severe gastroparesis, and even death. Because the patient sadly and slowly starved to death. This last example actually happened two weeks ago. Believes just as you do. Morbidly obese, different conversation. 10 to 30 pounds, diet and exercise.
You know, I'm sure you've seen that a bunch of articles just came out in the media. There are thousands of lawsuits against these medications. People are having ocular strokes. I've never even heard of such a thing. What is an ocular stroke? Essentially, they're spontaneously going blind. Now, that I have heard of as a side effect.
I don't understand the mechanism because it's actually not on the box with regard to side effects. So I don't know what the mechanism would be, but it is happening. There's a vision issue. This is far more extreme than what's represented in the side effects. One woman said her colon popped. I don't even know what that means. I, honest to God, couldn't even begin to tell you.
But what I can explain to you is that one of the ways in which this medication works is to delay gastric emptying, which means food will sit in your gut for a long time. If you take these medications consistently, which you have to do because they know that if you get off of it, when I say they know, I'm referring to meta-analyses. Right. Ever done.
If you get off of this stuff, you gain it all back on. It is a marriage. It is not a fling. It's a commitment. Well, if you're constantly over days, months, years having food sit in the gut and exiting at an extremely delayed pace. Imagine what that's going to do. That's the gastroparesis, stomach paralysis. That's what they're talking about. The food is no longer moving through the gut.
And then you get intestinal blockage, right? So stuff's getting stuck in there. Why? Because it's not moving through the gut. You get gastric bezoars, which we've talked about before, which are these balls that look like a cat puked it up in the gut. I mean, it's pretty serious. So I would simply say... Morbid obesity is pretty serious, right? Yes. There's no judgment here.
If you have a food addiction, if there's a psychological component, if there's no way forward and your health is already greatly compromised, this is a conversation with your doctor. But people that are taking these things to get ready for a summer vacation, it's like, dude, you are dancing with the devil. For what? To go from a six to a two? And again, There are things that are observational.
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Chapter 8: How does identity politics affect book publishing today?
And then what ends up happening, and I'm not saying this has happened with her. I have no idea.
We don't know if it's GLP-1s, if it's this parasite she said took hold of her face.
Let's say it was GLP-1s and she lost a lot of weight, but then what ends up happening is people end up putting... a bunch of filler in their face. Right. And I don't know if you and I have ever discussed that one, but that's a completely separate ball of wax. And it is a really bad idea.
I, you know, every couple of years, I pull a couple of CCs out of my right butt cheek, next two years, left butt cheek. I'm due actually getting a little thin right here. And you put your own fat in your face, man. Like I, I'm just being honest. It is, it is far safer to, Your face will look much better. You know, yes, it's more expensive.
You know, a lot of the fat will go away, but some will stay. And the reality is if you're looking for something cosmetic because you got too thin or you're underweight or you're just getting older, that is the, it's the only way to do it because not only are they going on these weight loss medications, which is accelerating aging, but
destroying the muscles in their face, arguably dampening those subdermal stem cells, which is what makes the skin look more youthful and actually behave in a more youthful fashion. But then they put all this dead garbage in their face, like filler, and it's a compounding problem.
The other one we have to look at is Kelly Osbourne. Before and after the after photo. No way. No, no, no. That's from Instagram. No, it isn't, dude.
No, it can't be real.
Are you serious? I know. I know. You think it can't be real. Are you kidding? That's real? No, that's real.
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