Bryan Johnson & Kate Tolo On Curing Their Incurable Diseases, Addressing The Disparity In Women's Health & The Don't Die Mission
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What are the opening sponsor messages and the premise of the episode?
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If we are to be don't die, we both have to cure our incurable diseases. So either they get us or we get them.
Anti-aging entrepreneur Brian Johnson revealed a recent diagnosis of autoimmune
gastroidis. Kate Tolo is the most measured
female in history. One of the sharpest content minds, Kate pitched Brian's what if the science experiment was done in public.
So we're spending $2.6 million on my protocol. And I was like, oh yeah, I think I have suspected endometriosis. Brian hears about it and I was diagnosed in something like 42 days. Women typically take six and a half years to get a diagnosis.
I think it's possible that we have a cure within like six months. This has never been done before. We've done all of this in four weeks time.
There's a perception that this is about you wanting to live forever.
I can't understand what living forever means. I simply want to say yes to existence. And what I really concluded is that
Super nice to be here, you guys. Thank you for inviting me into your beautiful home, into the sanctum. Uh, I'm excited to talk to both of you together. Uh, and my first question really is for Kate, like, I just want to know, like, what is it actually like to be in a relationship with this lunatic?
Yeah. To look over and you're just smiling. Just, you
know, have at it.
Yeah. Um, it's a lot. It's definitely different. Um, Brian is a unique, special human being and I've known that since day one, since the m first moment I looked into his eyes. And honestly, I feel like it's out of my control. I don't think I am in charge of whether or not I love Brian. My body just does. And so
what what is your kind of like relationship history prior to this? Like in terms of like other guys that you dated and and the kind of delta between that and the experience of like living with Brian?
Yeah, I mean I think Brian's just one of a kind. So I would categorize myself generally, like both in relationships but also lifestyle, how I think about the world as a fairly normal Average Bellcurve person prior to meeting Brian. And so even in just the way I live life now, it's entirely different.
Initially you were you came in like as an employee, right? Like you were working here for quite a while, right? Before the relationship uh blossomed. What attracted you to want to be in his employee to begin with? Like what was it inside of you that like wanted to be part of this whole thing?
It was his neurotech company that I fell in love with so deeply. I was twenty one. I just moved to New York. I had grown up in a small town with immigrant parents. So I didn't have a ton of exposure to like What is an engineer? And you know, what's a consultant? Like that those words just didn't mean anything to me. I got to New York.
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Chapters
6 chapters
1
What are the opening sponsor messages and the premise of the episode?
0:00–8:38
2
How do Bryan and Kate describe their “Don’t Die” mission and the recent diagnoses that sparked it?
8:38–1:01:36
3
What guardrails does the conversation propose for prioritizing human existence?
1:01:36–1:11:38
4
How do Bryan and Kate define an “anti‑entropic system” and why do they see religion as a model?
1:11:38–1:20:43
5
Why does Kate describe herself as “legibility‑challenged” and how does that affect her relationship with others?
1:20:43–1:42:24
6
How do the hosts confront the reality of death, aging parents, and the cultural aversion to mortality?
1:42:24–1:59:24
Speakers
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