In this episode, Dr. Brandon & Dr. Morgentaler talk about mismatched sexual desire in relationships and why recent claims linking testosterone therapy to heart attacks, strokes, or death don't hold up to real science. 00:00 Introduction and Viewer Question – Dr. Brandon & Dr. Morgentaler introduce the episode and read a listener question about feeling pressured when partners have different sex drives. 00:30 Addressing Desire Discrepancy in Relationships – They explain why mismatched libido is normal and share practical ways couples can reduce pressure and resentment. 06:39 Debating Testosterone and Cardiovascular Risks – The discussion shifts to a recent article claiming testosterone therapy may raise heart risk and why that claim raised red flags. 16:44 Analyzing Cardiovascular Risks in Testosterone Studies – Dr. Morgentaler breaks down what high-quality trials actually show about testosterone and heart attacks, strokes, and death. 19:11 Flaws in Study Design and Data Interpretation – They explain how poor study design and mixed populations led to misleading conclusions in the paper. 24:27 Conclusions and Implications for Future Research – The episode wraps with why testosterone therapy remains safe when properly prescribed and why single studies should not drive fear. Resources: TRAVERSE Trial (FDA-mandated RCT): Largest testosterone study to date showing no increased risk of heart attack, stroke, or death 2013 JAMA Study (Vigen et al.): Early study that sparked concern about testosterone and heart risk, later criticized for major data errors 2026 Journal of Sexual Medicine Study: "Dissociation Between Testosterone Replacement Therapy and Cardiovascular Events in Men" (critically reviewed in this episode) Multiple Meta-Analyses & Randomized Controlled Trials: Consistently show no cardiovascular harm from testosterone therapy With Dr. Abraham Morgentaler and Dr. Marianne Brandon Listen to the podcast on all of your favorite platforms: Apple: https://podcasts.apple.com/ec/podcast/the-sex-doctors/id1761813985?l=en-GB Spotify: https://open.spotify.com/show/0apSFzquJXKoOGnmI6ndgT?si=e5a1e482c7ca46c7 Find us on: Instagram: https://www.instagram.com/thesexdoctors?utm_source=ig_web_button_share_sheet&igsh=ZDNlZDc0MzIxNw== Facebook: https://www.facebook.com/thesexdoctors YouTube: https://www.youtube.com/@thesexdoctorspod TikTok: https://www.tiktok.com/@thesexdoctor LinkedIn (Dr. Abraham): https://www.linkedin.com/in/abraham-morgentaler-md-81628b6 LinkedIn (Dr. Marianne): https://www.linkedin.com/in/mariannebrandon-59224513 X (Dr. Abraham): https://x.com/DrMorgentaler X (Dr. Marianne): https://x.com/drbrandon #SexualDesireDifferences #TestosteroneTherapy #HeartHealth

Ask this episode

“What did the council decide on item 42?” — answered with the speaker and the moment.

Transcript

Related