Sponsored by Ceva. Head to dvm360 Flex and login or create a free CE account and claim your credit after listening to this episode. Program Description: During this podcast, we will discuss the innovative new science behind the Douxo® S3 line by Ceva specifically focused the new to veterinary medicine active ingredient, Ophytrium®. We will discuss the basics of cutaneous structure aka the epidermal barrier function as well as the cutaneous immune system and response and finally the cutaneous microbiome. These 3 different systems all play a role in many different dermatologic diseases which plague our veterinary patients. Learning Objectives: Better understanding of the 3 skin barriers: epidermal barrier, immunological barrier, and microbiological barrier Understand how all three of these barriers are disrupted in allergic disease leading to itching Know how Ophytrium® works to repair these barriers Program Agenda: Introduction of Ophytrium® – how and why it was chosen as the active ingredient in the innovative S3 skin care line. Review of cutaneous structure and the epidermal barrier with focus on how this structure is involved in the development and progression of allergic skin disease Review cutaneous immune system and response with focus on the atypical immune system response which occurs in allergic skin disease Discuss the current understanding of the cutaneous microbiome and how/why dysbiosis occurs Review how topical Ophytrium® interacts with each of these 3 different aspects of the skin

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