In this podcast we talk to one of the principle investigators of the EPIC study, Professor Adrian Boswood. We discuss the findings of the evaluation of pimobendan in dogs with cardiomegaly caused by preclinical mitral valve disease. Why not go to the Journal of Veterinary Internal Medicine’s website, download it and have a read now! http://onlinelibrary.wiley.com/doi/10.1111/jvim.14586/full It is not often that a single paper has the ability to radically change clinical practice. This epic study has overwhelming evidence that pimobendan administration before the onset of clinical signs in dogs with mitral valve disease (MVD) prolongs the preclinical period by 15 months. The dogs were identified by having a ≥3/6 grade systolic heart murmur, echocardiographic evidence of MVD, and radiographic or echocardiogram evidence of cardiomegaly. You can also see a video of Professor Boswood discussing this study on youtube https://www.youtube.com/watch?v=wtzr1E3V-gE and an infographic too https://www.youtube.com/watch?v=5qxHMGZ-9aU It is indeed EPIC. If you have any comments about this podcast, please get in touch (email [email protected]; tweet @RoyalVetCollege using #rvcpod; or use the RVC facebook page). We would greatly appreciate your time to rate us on iTunes and write a review

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