Septic shock management is complex, and many poor outcomes stem from preventable management errors rather than delayed recognition. In this episode, we break down the most common mistakes clinicians make when managing septic shock, using a physiology-driven framework relevant to both the emergency department and ICU. We discuss pitfalls related to fluid resuscitation, delayed or inappropriate vasopressor use, treating mean arterial pressure instead of tissue perfusion, missed right ventricular failure, and delays in source control. Throughout the episode, we emphasize reassessment and escalation strategies that help avoid persistent hypoperfusion and organ dysfunction. This episode is designed for emergency medicine physicians, intensivists, residents, and trainees looking for a practical, bedside-focused approach to septic shock management beyond rigid protocols. Link to YouTube Video: https://www.youtube.com/watch?v=LktPBGHtn10 📚 Download the PDF study guide for this video: 👉 https://www.patreon.com/c/WhiteBoardMedicine Patreon members get access to mini-courses, study guides, practice questions, ad-free videos, and in-depth educational discussions designed for emergency and critical care clinicians. Disclaimer: This content is for educational purposes only and does not constitute medical advice. Clinical decisions should be made by licensed healthcare professionals using their clinical judgment, institutional protocols, and current evidence. Whiteboard Medicine assumes no responsibility for clinical outcomes.

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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