In this high-yield medical education podcast, we break down milrinone, a phosphodiesterase-3 inhibitor used for inotropic support in heart failure and cardiogenic shock. Whether you're in the ICU, ED, or cardiology service, this is your focused review of how milrinone works and when to use it. 📌 In this podcast, you’ll learn: What is milrinone and how does it work? Mechanism of action: PDE-3 inhibition → ↑ cAMP → ↑ inotropy and vasodilation Receptors and intracellular signaling explained simply Clinical indications: acute decompensated heart failure, cardiogenic shock, post-cardiac surgery Differences vs. dobutamine Side effects: arrhythmias, hypotension, renal clearance issues When milrinone is preferred in low-output states Evidence summary + board-style practice questions 🎯 Perfect for learners preparing for USMLE, Step 2/3, critical care boards, internal medicine, or pharmacy rounds. 📚 Related Resources: Download our milrinone study guide and practice questions: https://www.patreon.com/collection/1443765 Watch next: Playlist Vasopressors and Inotropes: https://youtube.com/playlist?list=PLf5bMa9_tvRg_nAnm91hsyHhI0y_ahoS1&si=Myz25vHJgHAp4Nvc 📰👇SIGN UP FOR OUR FREE WEEKLY NEWSLETTER👍👍 https://whiteboardmedicine.kit.com/634ccbe783 👍Become a WhiteBoard Medicine member for early access and perks! https://www.youtube.com/channel/UCiMhM7xCTT8b5SJRnhpH7Ag/join 👇DON'T MISS OUT - JOIN OUR PATREON COMMUNITY TODAY 👇 https://www.patreon.com/WhiteBoardMedicine DISCLAIMER THIS PODCAST DOES NOT PROVIDE MEDICAL ADVICE. The information, including but not limited to, audio, text, graphics, images and other material contained on this website are for informational purposes only. No material on this site is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified health care provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read, watched, or listened to on this video, or any other videos, reports, texts tweets or other sources.

Ask this episode

“What did the council decide on item 42?” — answered with the speaker and the moment.