Nikki Glaser talks about the trials and tribulations that women go through to get ready for an event, hers specifically was The Tonight Show w/ Jimmy Fallon. Her mom and sister are in town and they reveal how exhausting it is to hang out with Nikki. Friends of the show Andrew Collin, Ian Fidance and Tommy McNamara are in. We also meet Nikki's friend from St. Louis, Sean O'Brien, who talks about the worst thing that Nikki ever did to him. Liza Treyger and Doug Benson talk to Nikki and Tom Thakkar about the first lie that parents ever tell us. British comic sensation Simon Amstell shares the story of finding his comedic voice through a mushroom trip. Last but not least, Melissa Villasenor dishes about getting the call for SNL and the simple way she celebrated her new gig! SUBSCRIBE NOW for the best stuff from You Up w/ Nikki Glaser and listen every Monday thru Thursday at 10am Eastern/7am Pacific on Comedy Central Radio, SiriusXM, channel 95! Learn more about your ad choices. Visit megaphone.fm/adchoices

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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