肺炎支原体 (MP)是儿童社区获得性肺炎的常见病原体之一,秋冬季节往往是高发季,今年感觉更多。今年8月份以来,支原体肺炎以及与该疾病相关的治疗方式、治疗用药多次出现大范围的讨论视野中。“阿奇霉素”“支原体肺炎联合用药方案”“抗生素耐药性”等词汇多次登上热搜。借着支原体肺炎爆发,这一期我们大概聊了: 为什么支原体肺炎会在今年爆发? 应该不是今年爆发,而是在新冠流行结束后的秋天爆发 外在病菌的竞争优势以及人体内部的抗体的驯化 小朋友从出生以来没使用过抗生素,为啥也会耐药 抗生素对抗病菌的原理 抗生素是什么 抗生素怎么抑制病菌的生长 抗生素的分类和不同种类的作用原理 人类和动物的抗生素的滥用 病菌耐药后再次跨种传播 抗生素耐药性的内在逻辑 给大家一些建议 抗生素使用需遵医嘱,尽量先检查确定病原体再使用 最后我们聊了聊Alfa的近况温馨提示:本期提到的各种抗生素均为处方药,使用请谨遵医嘱。#song listCello Suite No. 1 in G Major, BWV 1007:I. Prélude - Janos StarkerHeartburn - Marco SfogliLove From Me - Johnson RodgieCarlos Gardel, Alfredo Le Pera: Por Una Cabeza - Martynas参考文献:[1]许沙沙,郭连峰,吴妍,张建东,马忠正,张长庚.儿童肺炎支原体肺炎临床特征和流行病学分析[J].中华医院感染学杂志,2017,27(14):3307-3310.[2]王亚翠,吴喜蓉,刘芳,尹青琴,李洁琼,王咏红,全舒婷,田雪,徐保平,申阿东.2016年至2019年北京住院儿童肺炎支原体感染流行病学特征和耐药性[J].中华实用儿科临床杂志,2022,37(14):1082-1085.DOI:10.3760/cma.j.cn101070-20210926-01159.[3]徐梦华,柳鹏程,卢丽娟,苏犁云,曹凌峰,徐锦.COVID-19流行期间上海单中心儿童肺炎支原体和沙眼衣原体感染流行病学研究[J].中国循证儿科杂志,2022,17(04):290-295.BARSCHKETT M,KOLETZK0 B,SPIESS C K.COVID-19 associated contact restrictions in .[4]Germany:Marked decline in children's outpatient visits for infectious diseases without increasing visits for mental health disorders.Children (Basel).202189):728.[5]FUKUDA Y,TSUGAWA TNAGAOKA Y,et al.Surveillance in hospitalized children with infectious diseases in Japan;Pre-and post-coronavirus disease 2019.J Infect Chemother,2021,27(11):1639-1647.[6]LEE H,ALLIE E,THOMAS H,et al.Respiratory syncytial virus;paying the immunity debt with interest.L ancet Child Adolesc Health,2025(12):e44e45.
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