Mendelian randomization

concept
7 mentions 4 recordings first heard Feb 2025 last heard 18 Mar ↓2 vs the 6 months before

Mendelian randomization is a genetic epidemiology method used to infer causality between risk factors and disease outcomes.

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The Last Show with David CooperSocioeconomic Status Alters Your Brain Structure · 1:33 · 18 Mar
…And the reason we wanted to get a genetic measure of socioeconomic status is so that we could perform a technique called Mendelian randomization.…
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The Peter Attia Drive#380 ‒ The seed oil debate: are they uniquely harmful rela... · 57:57 · 19 Jan
…Okay, do you want to talk about Mendelian randomization through the lens of LDL?…
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Dr. Peter AttiaThe Peter Attia Drive · #344 - AMA #70: Nicotine: impact on cognitive function, perf... · 14:49 · Apr 2025
…I know we talk about these a lot, but I always think it's worth explaining what an MR is. So a Mendelian randomization says, let's look at genes in the population, which we can assume are randomly assorted. That's the randomization part. And let's ask the question, will these genes be a proxy…
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Dr. Peter AttiaThe Peter Attia Drive · #344 - AMA #70: Nicotine: impact on cognitive function, perf... · 14:24 · Apr 2025
…I just want to always point out, whenever we're talking……
Dr. Peter AttiaThe Peter Attia Drive · #336 - AMA #68: Fasting, well-balanced diets, alcohol, exerc... · 21:13 · Feb 2025
…So you might look at genes that control cholesterol or……
Dr. Peter AttiaThe Peter Attia Drive · #336 - AMA #68: Fasting, well-balanced diets, alcohol, exerc... · 20:53 · Feb 2025
…is, at least according to the epi, a minimal increase……
Dr. Peter AttiaThe Peter Attia Drive · #336 - AMA #68: Fasting, well-balanced diets, alcohol, exerc... · 20:26 · Feb 2025
…which is the Mendelian randomizations typically come up with a……
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