Alan Aragon

speaker
1,513 appearances 3 recordings 2 series first heard Aug 2025 last heard 27 Mar

Alan Aragon’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months
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Recordings per month over the last 12 months — 2 in all, peaking in Mar 2026 with 1.

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There just has been a massive accumulation of studies showing that it works great.
So the intermittent fasting variants, we have one we talked about earlier, time-restricted eating.
And we've got every other day fasting.
And then the other third major variant would be twice-weekly fasting or the 5-2 type of model.
And then you have consecutive-day fasting type of models as well, which are less studied because there's more risk involved in them.
And it's tough to incur that risk in research.
When you bring up autophagy, that's where I kind of have to push back on not on your –
your mentioning of it specifically, but just in general, people will say, or they'll make claims that autophagy, and we can say that, we can explain autophagy as a way that the body gets rid of parts of damaged cells.
It's an important process within the body, and it is a catabolic process or a breakdown process.
But the thing is,
It happens in a caloric deficit, regardless of whether fasting is involved or not.
Really?
Yes.
You maintain hypo caloric conditions, autophagy ramps up.
You can have a linear hypo caloric model or a non-linear or intermittent hypo caloric model.
And you'll get similar degrees of autophagy if you match the caloric deficit by the end of the week.
Now, the other interesting thing about autophagy is that you can ramp up autophagy through exercise.
And not only that, but both major types of exercise will increase autophagy.
So resistance training increases autophagy.
Endurance aerobic type training increases autophagy.
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