Alex Smith

speaker

32,670 appearances 416 recordings 1 series first heard Oct 2016 last heard 4d ago

Alex Smith’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 42 in all, peaking in Apr 2026 with 5.

Appearances

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GeriPal - A Geriatrics and Palliative Medicine Podcast · Longevity Treatments - Snake Oil or Breakthrough? John Newman & Mahtab Jafari · 23 Jul 2026 podcast

lives, people who are living with cognitive impairment, who also have the ability to live rich, full lives, people who are nearing the end of their life, who still can grow in important ways near the end of their lives. podcast-host

So I think both can be true at the same time. podcast-host

And one of the issues with the longevity focus and the relentless focus on, you know, being youthful as long podcast-host

as possible is that the flip side of that coin is that there can be a a stigma of aging, ableism around you know, living with cognitive impairment, for example. podcast-host

So I just wanna say that it's not necessarily a question unless you have reflections on that as well. podcast-host

observe people for, you know, forty years from the initiation of the trial and then monitor their healthy years and their lifespan and health span? podcast-host

We podcast-host

Brazil. podcast-host

We talked about it that in Brazil with Eduardo Ferioli. podcast-host

Um people can listen to that podcast. podcast-host

We'll have a link in the show notes here. podcast-host

Yeah, John, do you but but many people won't have listened to it. podcast-host

So please let us what what's your understanding of intrinsic capacity? podcast-host

I'll give you the thumbnail sketch, but then podcast-host

Mm-hmm. podcast-host

Oh, we should get into what we would choose now. podcast-host

I think this is really interesting just to summarize what I'm hearing for our listeners who may not be familiar with this whole FDA approval process. podcast-host

Like we have really promising therapeutics that work in model systems like fruit flies. podcast-host

How do we translate that into medications that humans can use? podcast-host

Well, we do a a clinical trial, but you have to have an outcome of that clinical trial and you can't podcast-host

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