Longevity Treatments - Snake Oil or Breakthrough? John Newman & Mahtab Jafari
episode
GeriPal - A Geriatrics and Palliative Medicine Podcast
51 min
2 speakers
7 chapters
transcribed 10 hours ago
Transcript
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Transcript generated automatically by AI and may contain errors.
What is the main focus of the Longevity Treatments discussion?
This podcast is not C Me Eligible. If people do want to learn more about C Me Eligible Podcasts, Alex, what do they do?
They can go to JerryPal dot org backslash CME.
And on to the show. Welcome to the Jerry Pow podcast. This is Eric Rudera. This is Alex Smith. And Alex, we're going to be talking about longevity long pronounce it. Longevity. Longevity sights. I don't know what's wrong with my tongue today. Miracles or Snake Oils? That's gonna be the topic. Who do we have with us?
We're delighted to welcome Matab Jafari, who's a professor of pharmaceutical sciences and director of the UC Irvine Center for Health Spain Sciences. We met at the UCSF alumni reunion and you know, she was talking to me about how sh she had been approached by several media outlets about this or that longevity medication. I thought, oh boy, this would make a great podcast. So thank you so much for joining us, Matab.
Thank you for having
me. Zot za go and eaters. That's my uh yeah, that's my alumni right there. Oh, yeah. Undergrad. Yeah.
Anteaters. I didn't know that. Anteaters. Okay.
You can do two. That's that's
not Is that the sound an anteater makes?
How did Mahtab Jafari become interested in longevity research?
That is learning a lot on that podcast.
Yeah, you go you watch an anteater, they're just constantly zoning.
It's uh um and John Newman, uh, who has been a frequent guest on this podcast, is a geriatrician and geroscientist who works at the Buck Institute in Marin as well as UCSF. John, welcome back to the JerryPell podcast.
Yeah, thanks for having me again. And so much has changed since the last time we talked about this stuff. So
I'm excited to learn how to live forever.
Yeah, I think that was the song request the first time John was on. Who wants to live forever? Not easy to sing, that queen stuff, by the way.
So we got we're gonna lotta talk about. We'll be talking about why you guys got interested in this and uh uh what's the goalposts and what meds are promising and which ones potentially are snake oils. But before we talk about all of that. Song request? Who has the song request today?
I had the song of crest, although we had we had a mind milled on the song of Crest.
Yeah.
Well what is the song? Wake Me Up by Avici, which I love because to me it's it's a song about aging. It's a song about the tension between like you wanna you wanna keep this like vibrancy and the open horizons of youth. But but also there's a lot of stress of not knowing what's gonna happen and how you're gonna get through it. And when you're older, you have this self assurance, you know who you are, you've like you've done the journey. And but what if you could just meld the best parts together? And that's kind of what we're gonna talk about.
Oh, that's great. And Matab, you have a connection to this song too. You wanna share that with our listeners?
Sure. I was so excited then uh John uh suggested this song because I happen to know the songwriter and the artist Alo Black, who is uh one of my Absolute favorite people on this planet, not because he's an amazing artist, because he's also a great human being. So I I almost listen to this song, believe it or not, every day. I feel like I need to listen to it. It just calms me down. And uh with John's description of the song, now I have new insights. Now I'm going to listen to it a little bit more carefully, because he's right.
Well what is what is it actually about, according to the person who wrote it?
You know, everybody interprets it differently. And that's a good question. I should I should ask Alo that question. I've never asked him that question. He just knows that I this is one of my I would say this is my f favorite songs. I don't wanna say one of my favorites. It's like number one and then
Okay, before we raise the bar too high, let me play my little interpretation of the first person chorus. Here's a little bit.
Feel my way through the darkness. Got it by a beating heart. I can't tell where the journey went. But I know where to start. Tell me I'm too young to understand. Say I'm caught up in a dream. Life will pass me by if I don't open up my eyes. Well that's fine by me.
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Chapters
7 chapters
1
What is the main focus of the Longevity Treatments discussion?
0:00–1:11
2
How did Mahtab Jafari become interested in longevity research?
1:11–7:26
3
Why did the hosts choose “Wake Me Up” by Avicii as the song‑request for this episode?
7:26–20:54
4
What are the challenges of translating animal model results into human longevity therapies?
20:54–32:12
5
How can clinical trials be designed to evaluate aging‑targeted drugs without waiting decades for outcomes?
32:12–42:16
6
Which supplements and lifestyle interventions do the guests personally use for healthy aging?
42:16–47:40
7
Which longevity interventions are rated as very promising, meh, or snake‑oil by the panel?
47:40–51:28
Speakers
2 identifiedMore from GeriPal - A Geriatrics and Palliative Medicine Podcast
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