Catherine Haig
speaker
125 appearances
1 recordings
1 series
first heard May 2026
last heard 28 May
Catherine Haig’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in May 2026 with 1.
Appearances
It's Haig.
Thank you very much for inviting me on.
Yeah, I am a prion biologist.
My work has generally focused on the human forms of these diseases.
So in humans, most of the diseases, they're a bit more like Alzheimer's.
They arise for no known reason.
They're not all by any means due to infection.
That's a very, very small amount.
Yeah, there are a very small number that are genetic as well.
So in the focus on human diseases, what we developed was what we call a human cerebral organoid model of disease.
And so what that is, is we take a little snip of skin cells from a consenting donor and we reprogram them like you would a computer to make them stem cells.
And from those stem cells, we then tell them to grow into brain cells.
And we create these little balls of brain cells.
Once we've done that, we can expose them to those infectious prions from a human that died of these diseases.
And we can have them infected to model the development of disease in a Petri dish.
We use Creutzfeldt-Japob disease.
So that's the most common form of human disease.
It's still really rare.
It's an incidence of about one to three per million.
So not common by any stretch.
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