Catherine Haig

speaker
125 appearances 1 recordings 1 series first heard May 2026 last heard 28 May

Catherine Haig’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in May 2026 with 1.

Appearances

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But the people who die of it, the prions that are within their brain are infectious to other human tissue.
So that's what we use.
Yes.
Yeah.
And we've monitored them for the disease progression, what's changing in them, and the deposition of the misfolded protein that is that causative prion.
So we see all of that within the human organoids.
Well, like you said, the big question, what worries everyone, is the potential for a jump from the observance to humans of this disease.
And that's a really legitimate worry.
I don't know if you have covered mad cow disease on this show, but these diseases are in that same group, that same family.
So mad cow disease did jump from cattle to humans.
It was thought to be through eating contaminated meat.
So it's a real genuine concern.
So for us, we now have a model of human infection.
And we thought we could use this to try and test that species barrier.
Our model is somewhat artificial, to be fair.
we literally put the mini brains into a deer brain homogenous.
So those little mini brain organoid cultures swim in the CWD infectious prions.
It's a massive exposure and it's a prolonged exposure.
So it's far more than we would ever expect any human to really meet.
And certainly no human brain would be expected to be in that environment.
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