Dr. Abe Malkin

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151 appearances 1 recordings 1 series first heard Nov 2024 last heard Nov 2024

Dr. Abe Malkin’s voice in public audio — every appearance, attributed to the second.

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Habits and Hustle · Episode 395: Dr. Abe Malkin on Next-Gen Health: NAD Drip Therapy, Ketamine and Environmental Testing · 5 Nov 2024 podcast

So I think there's a physiological benefit of it and then also a psychological benefit. Learning how to manage your emotion around, I need to get out of this stressful situation right away rather than dealing with it, I think is an entirely different benefit other than the physiological benefit.

I'm certainly someone who like feels that way initially with tough situations, but learning how to manage that psychological pressure and overcome it and get through it is something that even if you have that initial cortisol spike, learning how to get through that and control your breathing and get through the experience, anyone can do it. It's just a matter of managing your emotions around it.

Yeah, well, I think just to catch people up, you mentioned peptides. Peptides are great. There's hundreds of different peptides for different functions. They're very targeted. There are peptides that can increase growth hormone. There are peptides that can reduce inflammation. There's peptides for sleep, for weight loss, for libido.

So for those who don't know a lot about peptides, talk to your doctor and learn about the various different types of peptides that can be beneficial. We talked a lot about NAD and Niagen earlier on. That is something that is kind of a core component of a good longevity strategy to replace that.

If you want to go a little bit deeper down the rabbit hole, there's things like exosomes and stem cells, which I'm sure people have heard about if they're interested in biohacking, but the way in which they're being used now are really amazing. So for years, people were doing intra-articular injections of stem cells and exosomes into the joints. So you...

you hurt your knee, you hurt your ankle, you hurt your elbow, you get an injection into the joint from your orthopedic surgeon. And that's great for tissue repair in a very local area.

But for anti-aging purposes, you can get an IV of exosomes or stem cells, and the cells themselves won't just treat a particular joint, but they'll actually travel throughout your body and regenerate different areas of your body that need regeneration.

For those who don't know the difference, stem cells are actual immature cells that are harvested from birth products at the time of birth and haven't differentiated into muscle cells, liver cells, brain cells. So you're giving your body a blank check to then produce whatever cells it needs.

So interestingly enough, you might find someone who has back pain and they get a stem cell infusion for their back pain, but those cells will actually travel also to their pancreas and potentially can help reverse some aspects of diabetes. So stem cells as a general category are really emerging as an incredible tool. Exosomes are the byproduct of stem cells.

So they're the milieu that a stem cell exists in. It's the growth factors, the RNA, the DNA that produce a very potent anti-inflammatory effect in the short term. So they don't grow tissue the way that stem cells do, but you use it very focally to help treat inflammation in the short term.

So I would say both of those, in addition to the NAD, the niagen, the peptides, are some really helpful anti-aging treatments you can look into.

The difference is here in the US, you're not able to expand stem cells. So what you harvest at the time of birth, that's what you can infuse into someone. Outside of the US, there aren't restrictions against expansion.

So they can take a group of stem cells, put it in the petri dish, grow it by a thousand times or 10,000 times, and then use those to... So you might find an infusion outside the US with... a factor of 10 times as many cells as you will get here. And so in that sense, it could be more effective, but the actual cells themselves are the same cells.

Yeah.

But there's also an argument to be made that expanding the cells, each time you expand, do you lose a little efficacy of that additional cell? So I haven't looked at the studies directly, but that's essentially the way to think about it.

Well, microneedling is very popular. Is that not what you had or is it actual like injections?

That's pretty invasive. I would say that you get a lot of benefit from microneedling with stem cells or exosomes. And that is micropunctures in the skin that if you put numbing cream on, you can barely feel the needle. And then 30 minutes later, you can get a microneedling treatment done. And it's extremely effective. You get a new glow on your skin after that.

Yeah, you massage them into the pores that you create. Oh, yeah, yeah, yeah.

It's also not as painful.

I also think like mental health is super important to your longevity. And there's a lot of work being done now by using psychedelics in mental health, especially ketamine, which is now FDA approved for the treatment of depression and anxiety and other mental health disorders.

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