Dr. Allen Bookatz

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1,037 appearances 12 recordings 1 series first heard May 2026 last heard 3d ago

Dr. Allen Bookatz’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 12 in all, peaking in Sep 2026 with 4.

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Health Optimization Medicine Podcast · The Real Cause of Endotoxemia: Leaky Gut Explained | HOMe #023 · 19 Aug 2026 podcast

The colonocyte hits this energy crisis. matched

No butyrate, so it drops its beta oxidation and it switches into anaerobic glycolysis. matched

Now, glycolysis barely touches oxygen, so all that unused oxygen leaks out into the gut. matched

Now, luminal oxygen climbs, and that's the real problem here is that it kills off those strict anaerobes that make butyrate and lets opportunities. matched

tunis like enterobacterae take over. matched

And that in itself then pries apart those tight junctions and proteins like zonulin and occlutin can't do their job. matched

Well, brace yourself, Docky, up. matched

We're gonna get into the nitty-gritty here. matched

So the HomeHope protocol runs in four steps, and every one of them is really guided by objective metabolomic testing. matched

So, step one, we want to quantify the holobiont metabolome. matched

That means we're gonna run stool metabolomics for the absolute concentrations of those short chain fatty acids, acetate, propranate, and butyrate. matched

Plus, we're gonna look at matched

Functional gut markers such as secretary IgA, pancreatic elastase, beta glucaronidase, and cal protected. matched

We're gonna check the plasma LPS or anti-LPS immunoglobulins like IgA and M, those antibodies, and we're gonna use those to confirm whether there's a presence of endotoxemia or not. matched

Step two, we're gonna go ahead and feed the mucosal specialists. matched

And we're gonna do that by bringing in targeted polyphenols. matched

500 milligrams of pomegranate extract for the elegantanins. matched

Plus, we're going to give some type of cranberry pro-anthrocyanins. matched

Cyanidins, I realize these are quite mouthfuls, which selectively are going to help feed and grow that acromantia and push the goblet cells to make that MUC2. matched

Step three, we're going to fuel the colonocytes directly. matched

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