Dr. Alok Kanojia (Dr. K)

speaker

1,658 appearances 5 recordings 3 series first heard Sep 2025 last heard 27 May

Dr. Alok Kanojia (Dr. K)’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 4 in all, peaking in Oct 2025 with 2.

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HealthyGamerGG · How Psychedelics Unlock Your Brain’s “Edit Mode” · 13 Oct 2025 podcast

If it crosses the middle, by the way, that means that there's not a statistically significant result.

So it basically doesn't show a benefit.

So what this means is that if we do one measurement, so if we do a single post measurement, so here you are before the psychedelic, here you are after the psychedelic, we see larger effect sizes.

But the moment that we add a placebo, what happens to this curve, right?

So we start to see that things shift to the right.

The value of the treatment goes down the second that you add a placebo control.

So this is a really good example of people will say, like they'll look at this study and they'll see, oh my God, it leads to 50% improvements, but half of that could be placebo.

As we get to more sophisticated trials,

The value of psychedelics seems to be going down.

So this is LSD.

Here's MDMA.

Here's psilocybin.

Right.

So what's really interesting is that once we add placebo control to psilocybin, it seems like it actually the effect sizes increase.

Ayahuasca, MDMA.

Here's MDD.

So this is depression.

So it seems like psilocybin is like quite effective for depression.

Here's MDMA seems to be not as effective for depression.

Ayahuasca is not effective for depression.

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