Dr. Alok Kanojia (Dr. K)

speaker

1,658 appearances 5 recordings 3 series first heard Sep 2025 last heard 27 May

Dr. Alok Kanojia (Dr. K)’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 4 in all, peaking in Oct 2025 with 2.

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HealthyGamerGG · How Psychedelics Unlock Your Brain’s “Edit Mode” · 13 Oct 2025 podcast

So since Adderall works right away, since I notice a difference, that sort of my brain sort of changes the calculation.

I don't need to get more into that, but I hope that sort of makes sense.

The more immediate effects are, the more we think something is effective.

This is why things like Xanax and opium and opioid medications feel like they're amazing because they hit us really fast.

And if they hit us really fast, the brain confuses that with being very effective.

So our brain confuses onset of action and speed of effect with magnitude of effect.

This is basically what I think is going on with microdosing, where a lot of people feel like they're doing better.

But if we look at a lot of the data that looks, if we look at studies that look at long-term effects, there seems to be a very small effect.

So let's take a quick look at a few studies.

So here's a study that's a systematic study of microdosing psychedelics.

So analyses of pre and post study measures revealed reductions in reported levels of depression and stress, lower levels of distractibility, increased absorption and increased neuroticism.

Notably, the effects believed most likely to change were unrelated to the observed pattern of reported outcomes.

Now, what does this sentence mean?

This means that what people believed changed is quite different from what actually changed, okay?

So let's take a look at another study.

So this paper is from 2019, so I thought I'd pull something up from 2024.

So perceptible drug effects were reported at doses of 10 to 20 milligrams, but not 5 milligrams.

This is an LSD microdosing study.

No serious adverse effects were reported.

Repeated doses of LSD did not alter mood or cognition on any of the measures studied, right?

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