Dr. Dan Pardi
speaker
617 appearances
1 recordings
1 series
first heard Jun 2026
last heard 25 Jun
Dr. Dan Pardi’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jun 2026 with 1.
Appearances
They're not as good as they used to be.
And so with creatine on board, creatine is doing a lot.
You can increase, if you have the right dose of creatine, so if you're taking somewhere like a loading phase, somewhere between 10 and even 20 grams a day, you're going to increase brain creatine source somewhere between 5 and 15%.
So let's just say like, you know, 10, 11% on average.
So not as much as muscle, right?
Muscle, you're increasing at about 20%.
But there's a variety of different mechanistic pathways that are of interest.
So improving bioenergetics, your brain's ability to sustain energy.
Neuromodulation, it might be a neurotransmitter.
I just created a reel for Instagram talking about
a new paper out of China that this group was looking to identify new neurotransmitters.
And after 12 years of looking and searching, they identified creatine as possibly a new neurotransmitter.
It fulfills a lot of criteria.
You find it in synapses, which is like the final communication structure.
It's released into the synapse.
We haven't found a creatine receptor yet.
That's important.
That's a missing piece of the puzzle.
But all these different criteria for something qualifying as a neurotransmitter seem to be present for creatine.
And the authors had speculated that
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