Dr. David Perlmutter
speaker
585 appearances
1 recordings
1 series
first heard Jul 2026
last heard 15 Jul
Dr. David Perlmutter’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.
Appearances
They go from using mitochondria to make energy to a very much less efficient way of making ATP called glycolysis.
So very much so, it is, I mean, I'm looking right now in my mind at the slides that I've made of the changes in the metabolism of these microglial cells.
The home run here is that the metabolism of these microglial cells
mirrors your body metabolism.
So everything you've been talking about for years, talking about metabolism, is absolutely on point now as it relates to directing the immune cells in the brain and charting your brain's destiny.
You are right.
It is really very much about our choices as it relates to our metabolism.
You brought up muscles and insulin functionality and driving glucose into cells where it can be used.
And the same thing happens very much so in the brain.
The brain becomes insulin resistant.
Some have called it type 3 diabetes, but that's exactly what is going on.
And
In that environment when insulin is not able to work efficiently in certain parts of the brain, not all areas of the brain are insulin dependent.
But interestingly, there are four areas that are insulin dependent.
The olfactory bulb, the prefrontal cortex, the hippocampus, and the hypothalamus.
What does that mean?
Hypothalamus regulates metabolism.
The hippocampus is our memory center.
The olfactory bulb is where our sense of smell takes place.
And the prefrontal cortex is the area involved in executive function.
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