Dr. Denise Marks
speaker
53 appearances
1 recordings
1 series
first heard Aug 2016
last heard Aug 2016
Dr. Denise Marks’s voice in public audio — every appearance, attributed to the second.
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Just before we freeze them, we remove a lot of the liquid and that removes the cryopreservation agent.
And so when the platelet is thawed and transfused into a patient, there isn't very much left and so any side effects are mitigated.
They saw how versatile and convenient the frozen blood products were.
They can keep a few fresh at all times, thought out, ready to go, and then if they have a mass casualty event, they can thaw out more blood products.
So the Australian clinicians realised that this was a capability that the Australian military could use to overcome the problems with the blood supply when they're deployed overseas.
If they've needed blood and the I guess the area that the military have been deployed to is close enough, we can send blood products, especially red cells.
So East Timor, for example, or the Solomons are close enough to send red cells, not platelets though.
then they would call on what is known as a walking blood bank.
And at the end of the day that's just other soldiers or personnel who are deployed to the area.
Instead of trying to reinvent the wheel, we went to the Netherlands and brought that technology back here to Australia and we adapted it for our blood products, which all sounds very easy on paper, but it was actually quite challenging.
The way that we collect platelets here in Australia compared to the Netherlands, it's reasonably similar, although our platelets are slightly more concentrated.
So what that means is there's more platelets in the platelet bag.
And this was making our platelets a little bit sticky when we thawed them out.
They were looking a little bit clumpy and we don't want to give clumpy platelets.
We want nice smooth looking platelets.
What we found was actually a very simple solution.
We just doubled the volume that we were freezing them in.
And we kept the platelets nice and warm the whole time when we were thawing them out and the problem was pretty much solved.
They have to be frozen at minus eighty?
So when you're packing them, you have to pack them in the right configuration with quite a lot of dry ice and we use special containers which we call shippers.
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