Dr. Eric Topol
speaker
954 appearances
18 recordings
4 series
first heard May 2025
last heard 14 May
Dr. Eric Topol’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 16 in all, peaking in May 2026 with 13.
Appearances
Now, some of it is lifestyle factors.
So if you have a diet, an optimal diet that doesn't promote inflammation,
And that would be a plant-based diet largely.
It would be avoiding as much as possible the bad ultra-processed foods that stimulate inflammation, avoiding too high a protein diet, which has been linked to promoting inflammation and atherosclerosis.
So a diet that's healthy is one thing.
The second is exercise is incredibly important for keeping our immune system intact.
and blocking untoward inflammation.
And then sleep, really important, deep sleep.
It's good.
Wow, that's great.
If you get deep sleep, you know, this is the ticket for getting those waste products out of your brain each night.
And as we get older, we tend to get much less deep sleep, that slow-wave sleep, usually in the beginning of the night.
So getting that, and you can work on that, but it's much more than just these lifestyle factors.
We've now learned that the immune system degradation with age, so-called immunosenescence, and inflammation, our propensity for that as we get older, inflammation,
These are the drivers of age-related diseases, and we can suppress them.
Like, for example, we talked about what can you do about Alzheimer's.
There have been three huge studies of the shingles vaccine, so-called natural experiments, in three different countries around the world.
Australia, Wales, and the U.S.
And what we saw from that was the shingles vaccine not only protects against getting shingles, which is bad enough, but it brought down dementia and Alzheimer's by 25%.
If that was a drug, that'd be extraordinary.
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