Dr. Kent Berridge
speaker
525 appearances
1 recordings
1 series
first heard Aug 2026
last heard 4 Aug
Dr. Kent Berridge’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Aug 2026 with 1.
Appearances
No, you're absolutely right.
Tolerance does develop, absolutely.
So yes, new users who take the same dose may die, whereas an experienced user, habitual user, is not.
Tolerance also is partly cue-controlled and context-controlled.
There is such a thing.
Where even an experienced user, if they take the same dose in a whole new setting, the dose that wouldn't really subdue them in the usual setting is more lethal in the new setting.
That's kind of conditioned tolerance.
But even a very experienced user who gets a crumb, you know, a fairly good crumb of fentanyl,
that's going to suppress – the tolerance is not going to protect them.
We don't kill them because we control the dose.
We know the dose.
Really?
Well, we say – that's right.
Because we kind of space out.
We say once you've earned it, now you have to wait a couple minutes.
It's a fast acting – it's a fast acting.
You have to wait 10 minutes before you get the next one.
Now you can – okay, now 10 minutes more.
Well, it's negligent, but it really hinges on the super potency of these new opioids.
You know, with heroin, it could be kind of predicted the dose effect and people knew what they were dealing with.
Showing 461–480 of 525 · page 24 of 27
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