Dr. Lauren Colenso-Semple

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771 appearances 1 recordings 1 series first heard Feb 2026 last heard 16 Feb

Dr. Lauren Colenso-Semple’s voice in public audio — every appearance, attributed to the second.

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Huberman Lab · The Most Effective Weight Training, Cardio & Nutrition for Women | Dr. Lauren Colenso-Semple · 16 Feb 2026 podcast

And so if we don't have to do that anymore,

Think about all the research we can do in women or in mixed-sex samples or in combined people on and off contraceptives, especially for sports science labs with fewer resources.

They can be part of that mission to do more research in women if we don't have to worry about what was a huge barrier historically.

Well, I've been involved in those more real-world gym-like program studies.

And with that increase in ecological validity, you –

sacrifice some of the measurements that you can do.

You take away some of that really tight control or within subject designs where you're having one leg perform one protocol and another leg perform another.

So I think there's a time and a place for both.

But if we want to look at molecular signaling, if we want to do these high

tighter controls where we just want to know that there was a sufficient exercise stimulus, and it's not necessarily about the fact that it was a leg extension versus a real-world leg training program, then...

those are better, because that kind of a study is not designed to say, and therefore, everyone should do unilateral leg extensions.

It's designed to say, under these conditions,

with this hormone profile or with this infusion of nutrition, then what happens to protein synthesis?

And that can be powerful and controlled in a way that a lot of the more translational exercise science studies are not.

So I think both are important, but it really depends on the research question as to which is the most appropriate design.

14 years, something like that.

It's definitely changed over the years.

I went through phases of really trying to maximize strength and I got injured a lot.

And then when I've been in phases of doing data collection

I've had to really scale back from my training because your schedule is not your own.

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