Dr. Mike Roberts

speaker
1,217 appearances 1 recordings 1 series first heard Jul 2026 last heard 8 Jul

Dr. Mike Roberts’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.

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And there was hypertrophy.
When looking at the biopsy markers, be it the estrogen receptor in the muscle or the angina receptor, there was zero, I mean, not even close association with hypertrophy.
Yes.
Oh, that's a great question.
So I and Yuha Atiyanen, he's a great colleague at Havascula.
He's the one that we did the conference with.
He and I organized on the response heterogeneity to resistance training for background information.
But he's also looked at this a lot.
He has shown that
That across the age span and skeletal muscle, you do seem to lose androgen receptor content.
And there does across the age span, young versus old.
This is where we get outside that just young window.
the relationship becomes a little bit more evident there in terms of less receptor could be detrimental to growing muscle, which we'll get to that topic too, because so far this conversation has hinged upon when we're young and vibrant and trying to optimize peak lifetime muscle mass, it doesn't seem to matter.
Things change at our age and beyond our future, right?
Proteins in the muscle may be a little bit more important.
And we have some data that I'll get into on that front too.
Instead of 20% in that young, vibrant, we're saying up to 20% of the variants could be related to the receptor thing.
When you become older, that explains more in terms of the response.
We are totally not there yet, dude.
That scares me because we actually have us in collaboration with Stu Phillips and Chris Vann was the lead on this.
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