Dr. Spencer Nadolsky
speaker
117 appearances
1 recordings
1 series
first heard May 2025
last heard May 2025
Dr. Spencer Nadolsky’s voice in public audio — every appearance, attributed to the second.
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Appearances
They're short circuits. They're frayed and fried. And that's why this GLP-1 medicines are so cool, because they seem to recircuit the brain in a way that... And again, it's not necessarily permanent. It recircuits it as long as you're taking the medicines, but it hits the receptors to basically stop the short-circuiting of the brain. So that's the pathophysiology. It's really related to appetite.
And people are like, but it's just energy balance. I'm like, yeah, the appetite drives the energy balance. And so that's the gist.
Yeah, I always like showing the other side of the coin. There are thin people that do not try to be thin. They're just thin. Are they choosing to be thin? No, they're just thin. They're eating crap. And people are like, yeah, but they just must have a faster metabolism.
Well, if you actually look at them, instead of eating five pieces or a whole piece of pizza, a whole pizza pie, they're maybe eating a slice or two and they're good. And they'll go and smoke their cigarettes and whatever. They're fine. And they'll drink some soda. It doesn't matter. They're not choosing to be thin.
So I think when you start thinking about it in terms of how biology works and how it drives our behavior, and of course, yes, the environment is super important because the environment is what changed over the past however many decades. Our biology didn't change, but the environment changed. then changed our biology once we gained the weight. And I think that's what people don't understand.
And I don't think, they just haven't been able to put themselves in those shoes. And again, the only reason that I kind of understand is because I did that bodybuilding thing and I was like, man, I was ravenous at just like a pretty high amount of calories.
Yeah. So here's what they're going to claim. They have some data that shows people stay at a certain job for however many years. What these places don't want to do is go, all right, we'll put in all the amount of money only for the next insurance to benefit from that medicine. So these are the games these insurances play. If we can figure that out, I mean, I don't know.
I have all sorts of different thoughts because some of me feels like, why don't we just make the drugs so cheap that people just pay cash?
And don't even worry about insurance.
They can figure it out. I know they can.
It doesn't make any sense.
I hate it. It makes me so mad. I'm like, oh, I guess we're all just going to fly to... to the UK just to get these drugs. Just so ridiculous.
So yeah, because here's what I see in the future and people have asked like, could everybody be on these? I think it's possible. And again, I'm not advocating that everybody should be on these. What I'm saying though is like, imagine a world where we're getting so good at like precision medicine and being able to predict
So like, sure, person that has the indication of obesity, we got to put them on and help them lose the weight. But what if we see that person's child and they're starting to go in that trajectory towards that same diseased obesity state? You could then target that person, put a little low dose and prevent that obesity from occurring in the first place and all the sequela that comes with it.
And ideally at a low price. So I do think, and the other thing is you said, why not use this technology? It's the same thing of like, is anybody using a horse and carriage? Sure. And like Pennsylvania, Amish country and things like that. But like, are you using your iPhone? Are you using a telegram? We're using technology. As long as it's safe, of course, that's what you got to make sure.
But I like to embrace it as long as it's good. And, you know, obviously we've been burned in the past. And you got to be careful there, but I say embrace it.
They're on all sorts of stuff.
It's weight bias. I think if people really... They really have to think deeply and it doesn't feel good to feel like, oh God, do I not like fat people type of thing? But that's... It's a weight obesity bias. If you really dig deeper, why not help them? I don't know. There's no reason not to.
So the way that I approach is basically I strongly recommend – I give – I have a program called LiftRx. I'm like anything. I don't care if it's one day a week. I don't care if it's 10 – you start off at like 5 to 10 minutes once a week. Please. And I will say most people like they – They want to. They want to.
And again, like you said, there's some people, the knee pain, they never felt like they could. They were just feeling miserable. But after you get them going, it takes some nudging. They start getting more physical activity, like at least walking and things like that. But ideally, if they're losing a large amount of weight, it would be ideal to weight train.
Showing 61–80 of 117 · page 4 of 6
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