Dr. Stephen (Steven) Klein

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467 appearances 1 recordings 1 series first heard Jul 2026 last heard 2 Jul

Dr. Stephen (Steven) Klein’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.

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RECOVERable: Mental Health and Addiction Experts Answer Your Questions · Ozempic and Cravings: How GLP-1 Drugs Work for Addiction · 2 Jul 2026 podcast

So some people started to study this.

There was a study run at Karen Treatment Centers that looked at opioid use disorder with once daily liraglutide that showed that people's cravings for opioids decreased by about 40%.

And then last year, a study was run on alcohol use disorder.

It was published in JAMA Psychiatry that showed that people decreased their drinking by about 40%.

pretty impressive data.

So it's been now the real push, I would say, the new frontier of addiction medicine is can these medications be repurposed as you opened for addiction or to treat other compulsive behaviors?

What's the answer?

I believe yes.

I think, you know, for me, I step back and I look at the data.

So I step back and I look at the studies that have come out, but maybe more nuanced.

I think most people with obesity and I'm talking morbid obesity where obesity is in BMI 35, 40, 45.

Those people really do have an addiction to food.

I think if you were to ask someone of a very high BMI the DSM-5 criteria for alcohol use disorder and change the word alcohol with food, many of the answers would be yes and their use would be severe.

I think based on that, they're already treating addiction.

For the first time, we may be getting to the actual core circuitry of addiction and not just treating the symptoms or the end receptors.

Yeah, so there was an amazing paper that came out about two weeks ago now in the British Medical Journal that showed that across multiple substances, GLP-1s have an effect.

So this was opioid use disorder, cocaine use disorder, nicotine use disorder, and alcohol use disorder.

So actually for the first time, this may be one of the...

only medications out there that seems to be substance agnostic.

So it can be used across the spectrum of addiction, again, because it's getting to more of the circuitry, less so the end product.

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