Dr. Tamiko Katsumoto
speaker
82 appearances
1 recordings
1 series
first heard Feb 2026
last heard 10 Feb
Dr. Tamiko Katsumoto’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Feb 2026 with 1.
Appearances
I'm a rheumatologist, so I take care of patients with arthritis, with a lot of other inflammation of other organs.
So rheumatoid arthritis, lupus, vasculitis, psoriatic arthritis, you name it.
I think arthritis is complex.
Basically, our joints are generally protected areas where you've got your bone, you've got a synovial lining, you know, you've got this nice joint capsule that is lubricated so that it allows us to move freely.
The problem is with inflammation, there can actually be a breach of those protective barriers such that you can end up getting inflammation.
There's actually a connection with the gut and mucosal barriers that play into the inflammation leading to arthritis.
Yeah, I think that, you know, it's actually I'm thinking about this.
There's a lot of analogies.
We talk a lot.
I know Zoe talks a lot about the gut and how there's this important lining of the gut.
Similarly, I think you can think about the joint in that there's an important lining called the synovial lining of the joint that can get breached when you end up having, let's say, T cells that are recognizing T.
some of the synovial proteins, so the joint proteins.
There can actually be what's called an autoimmune attack, where your own T cells can end up invading the joint, causing inflammation.
It causes a leaky joint, if you will.
We've heard about leaky gut.
And I think what we've started to learn over the course of many years of research is that these mucosal breaches, for example, in our gut, even in our mouth, our oral microbiome,
can stimulate certain bacteria that may actually cause our immune system to wake up.
T-cells that are attacking these specific bugs in our gut, in our mouth, can end up actually getting confused and attacking our joints.
So this is a whole hypothesis that's coming to fruition with some very exciting science recently in terms of how our immune system can be connected to joint inflammation.
Yes.
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