Dr. Tommy Wood

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1,133 appearances 1 recordings 1 series first heard Jul 2026 last heard 20 Jul

Dr. Tommy Wood’s voice in public audio — every appearance, attributed to the second.

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Huberman Lab · Accelerate Learning & Increase Cognitive Capacity | Dr. Tommy Wood · 20 Jul 2026 podcast

And with that improvements in executive function.

So aerobic exercise is gray matter and memory and resistance training is white matter and more sort of executive type decision making, processing speed type functions.

We talked about lactate and some of these other things that might increase BDNF with the aerobic training.

In resistance training, I think the primary mediator of that, or one of them, is IGF-1, which is particularly increased with resistance training.

We know that IGF-1 is really critical to the development of white matter, right in the womb and then as a baby.

And it seems to be also really important for white matter structure then throughout the lifespan.

So resistance training is a really great way to then create these boosts of IGF-1.

So that's probably part of why we see that difference.

But that's why...

you need to do both.

Though they may have similar kind of acute effects in terms of corrugative function, they seem to be having very different effects in terms of the structure and function of the brain long-term.

First of all, we talk about dementia, which is essentially the end stage of cognitive decline.

There's some trajectory of decline that happens from your peak to that point, where ideally we'd intervene much sooner.

But right now, we don't really do much until dementia is diagnosed.

But it's very similar.

We don't do very much until diabetes is diagnosed.

Ideally, we can act much earlier in that trajectory, and that's increasingly being accepted

in the neuroscience and neurology communities, that actually we could potentially change that trajectory or at least decrease risk.

And so within dementia, there is an umbrella term, which is essentially the loss of cognitive function such that you can't look after yourself on a day-to-day basis.

You can't do the basic activities of daily living.

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