Dr. Tony Wyss-Coray
speaker
644 appearances
1 recordings
1 series
first heard Feb 2026
last heard 23 Feb
Dr. Tony Wyss-Coray’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Feb 2026 with 1.
Appearances
is always a stretch.
And there's no clinical studies that show a clear benefit of fasting in humans.
And some studies in monkeys actually suggest that it's detrimental for monkeys to fast, for example.
They had more, I think, worse kidney function and things like that.
Overall, from animal studies, it's very clear that you activate sort of beneficial pathways.
They're very diverse.
Again, we can now use unbiased assessment of many different cell types in an organism at gene expression across thousands of genes.
And we see that different cells respond in different ways and you get functional improvements.
But they're very broad.
They're in part reduced inflammation.
Other cells, you get benefits on their energy metabolism, protein turnover, how they handle sort of what we call the garbage that accumulates in cells.
Overall, from these animal studies, clearly benefits from reducing calorie intake, also less what we call oxidative damage.
So it's like you burn a fire, right?
And if that fire is really intense, you may cause more damage.
But how you translate this really to tangible benefits in humans, I'm not sure.
Rarely.
I tried, you know, Longo's diet a few times where I reduce calorie, Walter Longo.
So it's mostly you switch to a ketogenic diet, so a fat-rich diet.
So your metabolism changes basically from a regular sort of glucose-driven diet to burning fat.
And you feel that when you start to starve, that somehow it's almost like your body changes a little bit and you get a bit more alert almost.
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