Dr. Tony Wyss-Coray

really one of these large clinical studies where you can then say, this actually works and could get FDA approval.

Have you done one of these?

I haven't.

I haven't.

Are you close with anyone who has?

I know people who have done it.

Yes.

And I know people who, as a response, actually then supported the research that we have been doing in this field.

There are companies now that offer this, what is called therapeutic plasma exchange.

And there was a small trial that was, again, placebo controlled in 40 individuals.

from a company called Circular Therapeutics.

And they then looked in these individuals, these are healthy older people, and they use some of these measures that allow us to assess how old the body is or how old an organ is.

called epigenetic clocks.

And they could indeed see that some of the organs looked younger or the body overall looked younger.

There's some improvements in function.

Not dramatic, but suggesting that there might be something there.

Yeah, yeah, yeah.

No, it totally makes sense.

And in a short answer, it's all of the above.

So what we see is with age, there's an increase in many of what we call inflammatory proteins.