Eric Topol

And then it dropped down to less than 5% after the black box warnings and all this stuff.

And in fact, I've had many patients, Jen, who've come to me in my cardiology clinic, women that said they can't get MHT from their gynecologist.

won't give it to them because of all these risks.

So you haven't changed over these decades of how you use, I mean, maybe the different preparations.

Absolutely.

I'm sure you're right about that.

Now, now that this black box has been lifted, perhaps not substantiated by the actual data, and perhaps not with a real review, it was a cursory

review, not a formal one.

What's your projection?

Is it now going to become back to where it was pre-WHI, where 30% or whatever more of women post-menopausal will get hormone therapy?

Yeah, no, that's very helpful, kind of putting that in context, because the information flow or misinformation is coming from lots of different directions now, as you're pointing out.

And we're going to get to wellness in a minute.

But before we do that, you actually touched on something, which is where you said a risk of, for example, blood clots.

And then there's, you know, women who have risk of breast cancer.

And there's women who are at risk of uterine cancer.

Right?

We don't do any polygenic risk scores or assess people at risk for osteoporosis or any of these things.

We could do those.

That is a formal genomic assessment, which is really inexpensive.

And we just go by their history.