Erin Allman‑Updyke and Erin Welsh (This Podcast Will Kill You hosts) - primarily Erin Allman‑Updyke or Erin Welsh

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917 appearances 1 recordings 1 series first heard Jul 2026 last heard 28 Jul

Erin Allman‑Updyke and Erin Welsh (This Podcast Will Kill You hosts) - primarily Erin Allman‑Updyke or Erin Welsh’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.

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This Podcast Will Kill You · Ep 217 The High Stakes of Cholesterol · 28 Jul 2026 podcast

Because that is when we see increased risk of a number of different diseases, but especially atherosclerosis, which is the fancy name for when cholesterol builds up in your blood vessels.

Okay, so cholesterol meaning these packages, these LDL packages specifically.

Well, yes.

So here's what happens.

When you have high levels of these LDL packages, or not just LDL packages, but other, like VLDL, like other cholesterol packages that are not HDL, okay?

Okay.

Non-HDL cholesterol.

If that's high levels in your bloodstream, then sometimes, because many of those particles, especially LDL packages, are small and sticky...

In our blood vessels, especially maybe at, say, bifurcations, like somewhere where your blood vessels split or a curvature or a place where you got damaged for some reason or another, those molecules can get stuck along the walls of our blood vessels.

And they get just underneath the first layer of cells into the wall of our blood vessel.

And once they are there, those packages kind of disintegrate.

And then you do have just free cholesterol molecules in the wall of our blood vessel.

And our immune system is like, whoa, dude, you're not supposed to be here.

You're only supposed to be inside of cells or attached to your little protein package.

What the heck are you doing here?

So our immune system triggers a huge inflammatory response.

And then that cycle basically can kind of continue.

More cholesterol gets stuck because there's inflammation in the wall of your blood vessel.

That triggers more inflammatory markers to come in.

And then over time, you get this buildup of actual free cholesterol, not just these packages, but like cholesterol floating underneath the wall of your blood vessel.

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