Erin Allman‑Updyke

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983 appearances 2 recordings 1 series first heard Sep 2026 last heard yesterday

Erin Allman‑Updyke’s voice in public audio — every appearance, attributed to the second.

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This Podcast Will Kill You · Ep 222 Vitamin K: Calling the shots · 22 Sep 2026 podcast

0 to 0.4 per 100,000 for late bleeds.

So very, very substantial decrease.

They often don't report the rates of early and classic bleeds because it's, I think, essentially zero.

And that's even true for oral prophylaxis.

So oral prophylaxis does a really good job at helping to prevent those early and classic bleeds.

But we still, depending on the study, because it's depending on

the exact dosage that was used and what the, like how often it was given and all of the different routes of oral administration in terms of timing, the rates can vary from like reduced, maybe one to one and a half per 100,000 to sometimes just as high as without any prophylaxis.

So about four and a half per 100,000 in some studies for late vitamin K deficiency bleeding.

So I don't have like good global numbers and,

I do really want to emphasize because I see this all over social media and it's kind of the same thing that we see with food dyes, which is so interesting.

This comparison of, well, in Europe versus in the UK, they do things differently.

They do the orals, which is so much gentler and more quote unquote natural.

I mean, none of it's natural.

Nothing in medicine is natural.

And

Guidelines across the globe prefer and recommend strongly for intramuscular vitamin K. The difference is that some specific countries still primarily use oral, though most professional societies and like

including European societies, the UK, the World Health Organization, the Canadian guidelines, the Spanish Association, and then a lot of individual countries like Denmark, Spain, Australia, Belgium, New Zealand, they all recommend this intramuscular dose.

But some of them have oral formulations that were approved by their regulatory bodies.

So that means that they have guidance on oral administration of vitamin K. It differs widely country to country, but they at least have guidance that they can give if a parent does not want the intramuscular formulation.

And that is not true in the U.S.

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