Isaac Saul
speaker
4,349 appearances
29 recordings
1 series
first heard Aug 2026
last heard yesterday
Isaac Saul’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 29 in all, peaking in Sep 2026 with 24.
Appearances
Our executive editor and founder is me, Isaac Saul, and our executive producer is John Long.
Today's episode was edited and engineered by Dewey Thomas.
Our editorial staff is led by managing editor Ari Weitzman with senior editor Will Kabak and associate editors Audrey Moorhead and Bailey Saul.
Music for the podcast was produced by Diet75.
To learn more about Tangle and to sign up for a membership, please visit our website at retangle.com.
All right.
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Thanks, Audrey.
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Isaac here with my dissent.
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So I agree with Audrey that GLP-1 use is a great choice for some people and will likely improve overall health throughout American society.
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Yet,
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I can't shake this concern that GLP-1s are just the latest rung on the ladder to a frictionless life.
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The AI chatbots do our thinking, the influencers summarize our news in one-minute videos, and GLP-1s shed light on our weight.
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There's no need to read, think critically, research, or exercise anymore.
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Shoot, even the bikes are now electric and do our pedaling.
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I have no idea if GLP-1s will have some long-term unseen downside, but given how many parts of our lives they impact, I suspect they will.
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People's personalities are known to change as well as other non-food related habits.
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Heart rates also increase and we don't yet fully understand any of this.
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I have a hard time finding GLP-1s encouraging in that larger context, and I'm inherently skeptical of any so-called miracle drug.
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But I mostly find myself worried about how few challenges people are overcoming on their own anymore.
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All right, that is it for my dissent.
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Showing 141–160 of 4,349 · page 8 of 218
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