James Bullen
speaker
1,082 appearances
27 recordings
1 series
first heard Nov 2017
last heard Feb 2020
James Bullen’s voice in public audio — every appearance, attributed to the second.
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Appearances
Health Report · Mini-organs, sex in aged care and mental health at the GP's office · 23 Sep 2019
podcast
Hello and welcome to the Health Report with me, James Bullen.
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Today, your mental health in the doctor's office and beneath the bed covers with baby boomers.
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But first we're headed to the lab to find out more about organoids.
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That's the term that's been coined for these tiny lab-grown organs.
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It's a new field of medical science that's only been around for ten years.
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Organoid researchers say these smidges of tissue could help us unlock fresh understandings about the origins of disease and help test new drugs.
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But this story is also about the real world consequences of benchide research and the promise of personalized medicine.
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Ruby's an ordinary 12-year-old.
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She plays netball, AFL, and dances.
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She's not a fan of maths class.
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And she has cystic fibrosis, a genetic disease that harms the lungs and the gut.
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That's Ruby's mum, Shelby.
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And she says the changes in Ruby's life are down to a new treatment she's been taking for the past three years, a drug called Ivocafta, trade name Kaleidico.
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But Ruby was only eligible for the drug because of the specific genetic mutation that caused her cystic fibrosis.
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And to understand what that really means, we need to understand a little more about the condition itself.
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Professor Adam Jaffy is the John Beveridge Professor of Pediatrics at the University of New South Wales and a respiratory pediatrician at Sydney Children's Hospital.
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When the gene works, cells produce a thin, watery mucus that acts like a protective lubricant.
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But when the gene doesn't work, cells make a thick, sticky mucus that clogs the body's organs and invites infection.
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It affects the whole body, but particularly the lungs and the gut.
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So, there are multiple different gene mutations that cause cystic fibrosis.
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Showing 221–240 of 1,082 · page 12 of 55
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