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James Smith

๐Ÿ‘ค Speaker
922 total appearances

Appearances Over Time

Podcast Appearances

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It was even something we might be able to realistically do in 10 years.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

I hadn't been tracking a lot of the developments going on in the synthetic biology field and learning about them.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

I was like, whoa, this is way further along than I would have guessed.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It was quite hard work.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It was a really busy time, but it was also amazing to get to work with such great people and people who fundamentally cared about what we were doing.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

These are people who previously, in a lot of cases, wanted to make Mirror Life, and now we're coming forward and saying this is something that shouldn't be done.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

So although there were a lot of hours, there were a lot of phone calls with many different people from all around the world,

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

it was really motivating to be a part of that group and to know that the way we talked about this was going to make a really big difference to how the issue went.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

So I was also pretty nervous because we had to make some decisions when we were writing up the paper about what recommendations we'd make.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

This, for many people, was kind of coming out of nowhere.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

And there's a different world where it could have been perceived as this crazy sci-fi risk and not taken seriously.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

And it was really important to avoid that from happening.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

So when the paper finally went up, we were kind of holding our breath to see how it would go.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

And I think, fortunately, it seems to have played out pretty well since then.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

Yeah, I mean, we thought a lot about this and there's a section in the technical report at the front, which I think does a really nice job of summarizing the top line thinking.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

But the main argument that I find most compelling is that by default, we were on track to make Mirror Life eventually.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

So a lot of well-meaning researchers had said this is something they wanted to do.

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

It had been this kind of

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

long-term goal of synthetic biology this interesting thing to aim towards for quite a long time and so by publishing the paper and drawing attention to the risks i think we were letting the conversation about what should be done happen much earlier than it otherwise might have

80,000 Hours Podcast
Why I quit everything to work on a biothreat nobody had heard of | James Smith, Mirror Biology Dialogues Fund

By default, people would have continued developing technologies relevant to mirror life, and then either we'd have just developed mirror life, which could have been really bad, or people would have spotted the risks nearer to that time, and then we'd have less time to deal with them.