Jason Karlawish
speaker
1,378 appearances
5 recordings
1 series
first heard Feb 2021
last heard Dec 2023
Jason Karlawish’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsNo recordings in the last 12 months.Older appearances are listed below; set an alert to hear about the next one.
Appearances
Second point.
Quest did what Quest did, you know, their test has its sensitivities and specificities.
They have access to physicians for people to talk and whatnot.
I think they probably want to bridge too far, but I do think it's only a question of whether or not when.
uh home testing becomes part of our world.
Uh 'cause this disease is a lot like other diseases where home testing is available, HIV, et cetera.
Highly identified highly identity transforming diseases tend to lend themselves to people to want to get the information on their own time and their own speed.
All right, let's set that aside.
I think the big issue here is just what you cited, which is the move which has been going on now for a good seven years as the science has advanced to define Alzheimer's disease on the basis of biology, period.
Um in a way to try and resemble other diseases uh such as cancer, diabetes, et cetera, that are defined quote on the basis of biology.
I I can't quarrel conceptually with it.
I think where the where the debate occurs is, you know, some of the sort of if you will, edge criteria, like as you said, what is the initial label that says this is Alzheimer's as opposed to not?
And right now it looks like AMOLED alone would make that criteria of you've got Alzheimer's.
The explanation for that is
Because amyloid is the initial biological event which leads to the cascade of developing tau and subsequently neurodegeneration.
So that's the logic.
It it's it it I get it, it's coherent.
But I think where I felt at the meeting when I watched the uh presentation of those criteria, I think what people were struggling with is is amyloid a risk factor that would lead to the subsequent development of the pathologic cascade, or is amyloid a disease marker?
What I found in the conversation
That had me confused is
Showing 381–400 of 1,378 · page 20 of 69
← Previous
Next →