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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
And I ask about that because if people had eating disorders when they're putting on their peak bone mass, that can affect their bone mass.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
Yeah, you bet I'm getting a DEXA for that person.
Ground Truths
Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
Absolutely.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
I don't need a polygenic risk anything to tell me that.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
I know that patient's at a high risk.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
I need to, you know.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
It's one of the biggest risk factors, absolutely.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
And I think that we need to do a better job of figuring out who should be screened earlier for osteoporosis.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
And unfortunately, the lack of data then gets translated by the U.S.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
Presentative Services Task Force as, well, we shouldn't do it.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
Okay, well, lack of data doesn't mean we shouldn't do it.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
Lack of data means we need to figure out how to do it.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
But I don't know how well those actually pan out long-term.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
Like, I think that, like, so for example, I'm a participant in the WISDOM study, and they gave us a polygenic risk score.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
But when I talk to a genetic counselor, I mean, they're now studying trying to decide
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
what does that actually mean long-term in the incidence of breast cancer mortality or breast cancer diagnosis or breast cancer screening?
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
So I don't know that we have, like, the long-term data to say what some of those risk scores actually mean.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
I mean, I could be wrong, but, I mean, from a breast cancer standpoint, I don't think we can tell people that it can raise or lower your risk, but we can't speak in absolutes.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
So I would tell people that we do not have the long-term data to answer that question.
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Jennifer Gunter & Eric Topol - Discuss Womenâs Health and Recent Changes by FDA for MHT
So it comes back to, like in everything in medicine, we need to individualize.