Jens Juul Holst

speaker

287 appearances 1 recordings 1 series first heard May 2026 last heard 4 May

Jens Juul Holst’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in May 2026 with 1.

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Discovery · The Life Scientific: Jens Juul Holst · 4 May 2026 podcast

And he said, OK, let's join forces and see what we can make out of it.

Because then we were able to create a laboratory and that laboratory was devoted to gut hormones.

And for this, the big thing was the new technology of radioimmunoassay, which had more or less recently been discovered or developed by two Nobel laureates.

And we adopted that technology as quickly as we could because that was necessary to study these gut hormones because they circulate in very, very low concentration.

So you must...

have a method of sufficient sensitivity.

And this new method had that.

There were no other methods that would be able to.

Yeah, our main interest became the regulation of the gut of insulin secretion.

And for me, that was logical because I came from this department that had specialized in peptic ulcer disease, you know.

And we had some peptic ulcer patients with too low blood glucose levels after we had been operating on them.

and we wanted to find out why that was.

We thought it would be a gut hormone, right?

So it was absolutely natural for us to find out how the gut regulates insulin secretion and glucose levels in the body.

So that became one of the key questions.

We put that up as a target for us, try to find out what are the increasing hormones.

And that's what actually we managed to do eventually.

Talk me through that process.

I was chasing this hormone that was responsible for the hypoglycemia in our patients.

And then a new peptide came up.

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