Jens Juul Holst

speaker

287 appearances 1 recordings 1 series first heard May 2026 last heard 4 May

Jens Juul Holst’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in May 2026 with 1.

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Discovery · The Life Scientific: Jens Juul Holst · 4 May 2026 podcast

So I was working very closely together with Michael Nauck.

from Germany.

And he was working in a diabetes hospital and with the big incretin expert in these days, Werner Kreuzfeldt, an important professor from Germany.

And together we arranged to have infusions made in his diabetes hospital.

People came in with really bad glucose regulation and gave them infusions of this new peptide for four hours and were able to completely normalize their blood glucose.

And that was really a breakthrough.

That was really a breakthrough.

Yeah, yeah, this is true.

And it didn't take long before we tried on type 1 also.

And it actually worked to some extent, not as well as in those with type 2 because it partly acts on the insulin.

And since people with type 1 diabetes do not have insulin, that part of the activity cannot be put into practice.

I see.

But they do have the glucagon problem.

And also there are many other things that improved with GLP-1.

So it actually works to some extent on people with type 1 diabetes.

And it's very interesting today.

Because the cardiovascular improvements that you get with GLP-1 and the anti-obesity effect, both of those are relevant for people with type 1 diabetes also today.

So that's why it's come back into the picture, you know, as something that really is of interest.

So this demonstration of the complete normalization of the glucose levels really meant that we convinced not only ourselves,

that this was a future therapy for diabetes, but also some of the pharmaceutical industries.

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