Lindsey Yourman
speaker
182 appearances
1 recordings
1 series
first heard Nov 2020
last heard Nov 2020
Lindsey Yourman’s voice in public audio — every appearance, attributed to the second.
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Appearances
And what I mean by that is when
We were looking at how long does it take for an older adult to benefit from a statin?
We looked at stroke.
We looked at all-cause mortality.
We looked at cardiovascular specific mortality.
And in the time period of the studies, usually they range from four to seven years, there actually wasn't a clear-cut, statistically significant benefit for those outcomes on their own, for all-cause mortality, for uh stroke.
Um, only a few of the studies showed benefit.
And uh for cardiovascular-specific mortality.
So, what that meant is for
us to think about how long does it take to benefit from a statin.
We had to look at all those outcomes combined, so called composite cardiovascular outcomes.
And so that's how we did it.
And if you if this each of the studies combines all of the potential cardiovascular outcomes, they could find a statistically significant benefit within the duration of the study.
So
Hopefully that answers the question of of what outcomes we looked at.
Those were things like a combination of anywhere from angina to resuscitation after a cardiac arrest to uh death from coronary artery disease.
So we looked at a combination.
Well, I think there's there's one study that was done by Jean Cottner and her friends at University of
Colorado Denver that uh really made an impression on me.
They had patients that were near the end of life, hospice eligible patients, I believe.
Showing 61–80 of 182 · page 4 of 10
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